Sentinel Node Lymphoscintigraphy in High-risk Cutaneous Squamous Cell Carcinoma

Pollock, Jondavid; Pollock, Ariel; Hardin, Rosemarie E.; Yousef, Michael; Nardo, Jayme; Polack, Edward P.

doi:10.1016/j.clsc.2017.04.006

Cited by 1 publication

(2 citation statements)

References 17 publications

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“…A more recent study which was conducted on this theme comes from Pollock and co. and was published in 2017; this time the study was focused on studying the importance of sentinel lymph node detection in high risk Merkel cell carcinoma patients (11). According to the same study group, the high risk lesions are characterized by a tumoral diameter larger than 2 cm, recurrent disease, high grade histological features, the association with peritumoral/perineural invasion and/or the presence of a larger than 4 mm in depth lesion.…”

Section: Studies Investigating the Effectiveness Of Sentinel Lymph Nomentioning

confidence: 99%

“…Therefore, the authors concluded that sentinel lymph node biopsy should become part of the surgical protocol in high risk patients (defined by a tumoral invasion higher than 4 mm and a diameter higher than 2 cm). Moreover, the authors pointed out the fact that after performing the sentinel lymph node biopsy in these patients, an upgrade of the stage of the disease was realized in 13% of cases, leading to the association of the adjuvant treatment (11).…”

Section: Studies Investigating the Effectiveness Of Sentinel Lymph Nomentioning

confidence: 99%

See 1 more Smart Citation

Merkel cell carcinoma – pro and cons aspects for sentinel lymph node biopsy

Bacalbaşa¹,

Bălescu²,

Dimitriu³

et al. 2019

Ro Med J.

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Merkel cell carcinoma represents an aggressive histopathological subtype of skin cancer with a high propensity to spread via lymphatic route. Once the benefits of the sentinel lymph node detection have been proven in malignant melanoma, the effectiveness of the method was investigated further on in Merkel cell carcinoma, as long as the two tumoral subtypes seem to have a common embryological origin. Surprisingly, the results reported so far in Merkel cell carcinoma are rather confusing, the method not being so far associated as part of the standard therapeutic protocol. However, it seems that the method plays a certain role in identifying the high risk patients and further tailoring the therapeutic strategy. This is a literature review of the most eloquent studies conducted on this theme.

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Section: Studies Investigating the Effectiveness Of Sentinel Lymph Nomentioning

confidence: 99%

Section: Studies Investigating the Effectiveness Of Sentinel Lymph Nomentioning

confidence: 99%