Sentinel Node Identification with Hybrid Tracer-guided and Conventional Dynamic Sentinel Node Biopsy in Penile Cancer: A Prospective Study in 130 Patients from the Two National Referral Centres in Sweden

Torbrand, Christian; Warnolf, Åsa; Glombik, Dominik; Davidsson, Sabina; Carlsson, Jessica; Baseckas, Gediminas; Håkansson, Ulf; Trägårdh, Elin; Geijer, Håkan; Kirrander, Peter

doi:10.1016/j.euo.2022.09.004

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…This discrepancy in the false-negative rate might have been attributable to different methods of SLNB and a distinct level of technique to detect and resect accurate SLNs among the studies, and further studies for evaluating the false-negative rate in penile SCC are needed [ 84 ]. The European Association of Urology guidelines recommend that patients with intermediate-risk and high-risk ≥ pT1G2 disease should undergo sampling of the inguinal nodes via SLNB or modified inguinal LND [ 85 , 86 ]. If SLN metastases are found, ipsilateral radical inguinal LND is recommended [ 86 ].…”

Section: Role Of Slnb In Skin Cancermentioning

confidence: 99%

“…SCCThe current NCCN guidelines recommend SLNB or inguinal LND for T1b or T2 lesions without clinically enlarged lymph nodes[69].Penil SCCThe European Association of Urology guidelines recommend that patients with intermediate-risk and high-risk ≥ pT1G2 disease should undergo sampling of the inguinal nodes via SLNB or modified inguinal LND[85,86].Anal SCCThe current NCCN guidelines do not recommend SLNB for either anal canal SCC or perianal SCC [96].…”

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confidence: 99%

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Role of Sentinel Lymph Node Biopsy for Skin Cancer Based on Clinical Studies

Ishizuki

Nakamura

2023

Cancers

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The sentinel lymph node is the first lymph node from the primary tumor. Sentinel lymph node biopsy (SLNB) is a surgical procedure that can detect occult nodal metastasis with relatively low morbidity. It may also have a therapeutic effect via regional disease control. The Multicenter Selective Lymphadenectomy-I (MSLT-I) trial revealed a prognostic benefit from SLNB in melanoma patients. However, it remains unclear whether there is a prognostic benefit from SLNB in patients with nonmelanoma skin cancer owing to a lack of randomized prospective studies. Nevertheless, SLNB provides important information about nodal status, which is one of the strongest factors to predict prognosis and may guide additional nodal treatment. Currently, SLNB is widely used in the management of not only patients with melanoma but also those with nonmelanoma skin cancer. However, the utilization and outcomes of SLNB differ among skin cancers. In addition, SLNB is not recommended for routine use in all patients with skin cancer. In this review, we provide a summary of the role of SLNB and of the indications for SLNB in each skin cancer based on previously published articles.

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Section: Role Of Slnb In Skin Cancermentioning

confidence: 99%

mentioning

confidence: 99%

Role of Sentinel Lymph Node Biopsy for Skin Cancer Based on Clinical Studies

Ishizuki

Nakamura

2023

Cancers

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“…A recent prospective study, conducted in 2022, underlined divergent results [ 83 ] among a total of 414 sentinel lymph nodes specimens. The authors reported a low identification rate based on fluorescence (85%) and a relatively high rate—compared to previous results—using blue dye (82%).…”

Section: Nirf-guided Robot-assisted Penile Cancer Surgerymentioning

confidence: 99%

Exploring the Applications of Indocyanine Green in Robot-Assisted Urological Surgery: A Comprehensive Review of Fluorescence-Guided Techniques

Licari

Bologna

Proietti

et al. 2023

Sensors

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This comprehensive review aims to explore the applications of indocyanine green (ICG) in robot-assisted urological surgery through a detailed examination of fluorescence-guided techniques. An extensive literature search was conducted in PubMed/MEDLINE, EMBASE and Scopus, using keywords such as “indocyanine green,” “ICG”, “NIRF”, “Near Infrared Fluorescence”, “robot-assisted”, and “urology”. Additional suitable articles were collected by manually cross-referencing the bibliography of previously selected papers. The integration of the Firefly® technology in the Da Vinci® robotic system has opened new avenues for the advancement and exploration of different urological procedures. ICG is a fluorophore widely used in near-infrared fluorescence-guided techniques. The synergistic combination of intraoperative support, safety profiles and widespread availability comprises an additional asset that empowers ICG-guided robotic surgery. This overview of the current state of the art illustrates the potential advantages and broad applications of combining ICG-fluorescence guidance with robotic-assisted urological surgery.

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