Sentinel lymph node biopsy with a gamma probe in patients with high-risk cutaneous squamous cell carcinoma

Abstract

The feasibility of determining SLNs using LS and an intraoperative gamma probe in patients with cutaneous SCC was shown. Unnecessary elective lymph node dissection and possible complications could be avoided in 19 patients.

Sentinel node biopsy for high-risk cutaneous squamous cell carcinoma

“…22,23 Our study found 6 of 26 cases (23.1%) to be SN-metastasis positive, which is within the range of past reports. No instances of regional lymph node metastasis occurred in the cases deemed SNmetastasis negative during the observational period in our study.…”

“…22 Excluding 5 cases that died of other diseases during the observational period, the remaining 14 cases survived and did not experience regional lymph node or distal metastasis. Further, Reschly et al reported that 5 cases of SN-metastasis negative cutaneous SCC survived without recurrence or metastasis and that 2 of 4 SN-metastasis positive cases (50%) died of the disease.…”

SLNB in cutaneous SCC: A review of the current state of literature and the direction for the future

“…A total of two of the 20 patients in this study with negative SLNB developed regional recurrence resulting in the death of one . Demir et al conducted a follow‐up on 14 SCC patients with negative sentinel nodes and found all were clear of regional and distant metastasis but one had local recurrence. Another follow‐up study on six patients with negative sentinel nodes yielded one patient with local recurrence and one with distant recurrence on follow‐up .…”

Sentinel lymph node biopsy for cutaneous head and neck malignancies

“…The 3-year survival rate was 100% for negative SLN and 21% for positive SLN [81]. Two additional small case series report no recurrence or disease-specific death in the negative SLN patients during the study of follow-up time [82,83]. These studies show promise, but they are small in nature with limited follow-up.…”