Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis

Lee, Sang-Soo; Yoon, Tae Young

doi:10.1016/s0303-8467(01)00111-1

Cited by 5 publications

(7 citation statements)

References 4 publications

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“…Some of these studies have suggested that the degeneration of the nerve endings (small fiber) was associated with the clinical manifestations of hypoesthesia observed in these pathologies. [16][17][18][19][20][21] In the case of GBS, the pathologic evidence of the nervous degeneration in the dermis also may be related to a worse prognosis of large fiber demyelinating disease. 19 These studies included only histologic studies of the nerve structures carried out by immunohistochemical techniques and not by hematoxylin-eosin.…”

Section: Discussionmentioning

confidence: 99%

Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus

Aguilar-Bernier¹,

Bassas-Vila²,

Torné-Gutiérrez³

et al. 2006

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus

Aguilar-Bernier¹,

Bassas-Vila²,

Torné-Gutiérrez³

et al. 2006

Journal of the American Academy of Dermatology

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“…In our literature review, mononeuritis multiplex was the most common type of peripheral neuropathy in LV patients 6,10,11,13‐18 . Mononeuritis multiplex involves injury of multiple peripheral nerves in multiple regions of the body and is commonly induced by autoimmune disease, systemic vasculitis, severe burns, diabetes, and infection; it may also occur as a paraneoplastic syndrome 14,20‐22 .…”

Section: Discussionmentioning

confidence: 93%

“…A total of 31 LV patients with peripheral neuropathy were identified. The articles included case series and case reports from eight countries: Japan, Korea, Canada, India, Brazil, France, Italy, and Portugal 3,6,9‐18 . Patients' age ranged from 22 to 80 years.…”

Section: Resultsmentioning

confidence: 99%

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Livedoid vasculopathy and peripheral neuropathy: A retrospective cohort study of 55 Chinese patients and literature review

Gao

Jin

2022

International Wound Journal

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Livedoid vasculopathy (LV) is a thrombo‐occlusive vascular disease with an uncertain aetiology. In addition to cutaneous manifestations, LV patients may develop peripheral neuropathy. This study aimed to examine features of peripheral neuropathy in Chinese LV patients. We retrospectively reviewed and analysed the clinical data of 55 LV patients treated at Peking Union Medical College Hospital and conducted a literature review of peripheral neuropathy in LV patients. The incidence of peripheral neuropathy in our cohort was 12.73%. Among the seven patients with neuropathy, five were women and two were men. Median age at enrollment and disease onset in these patients was 27.29 and 22.57 years, respectively. Mean time from the appearance of cutaneous manifestations to the development of neurological symptoms was 38.67 months. Peripheral neuropathy was generally refractory to treatment, asymmetric in the distal extremities, and slowly progressive. The main symptom was numbness; hypoesthesia and neuromuscular manifestations occurred occasionally. The proportion of patients reporting seasonal worsening of symptoms was significantly higher in LV patients with peripheral neuropathy than in LV patients without neuropathy (P < .05). Peripheral neuropathy is a potential complication of LV. LV patients with peripheral neuropathy require long‐term follow‐up.

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“…Perineuritis was first reported by Asbury in 1972 as distally dominant recurrent painful neuropathy characterized by inflammation in the perineurium (1). Other clinical symptoms and comorbid diseases were also reported (1-8,10). As our patient did not have any other malignancy or autoimmune disease, this case was diagnosed as perineuritis complicated with diabetes mellitus (7).…”

Section: Discussionmentioning

confidence: 99%

Perineuritis Successfully Treated with Early Aggressive Immunotherapy

et al. 2019

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Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms.

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Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis

Cited by 5 publications

References 4 publications

Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus

Presence of perineuritis in a case of papular purpuric gloves and socks syndrome associated with mononeuritis multiplex attributable to B19 parvovirus

Livedoid vasculopathy and peripheral neuropathy: A retrospective cohort study of 55 Chinese patients and literature review

Perineuritis Successfully Treated with Early Aggressive Immunotherapy

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