Abstract:Since Eijkman demonstrated, in 1897, that atrophic degeneration of the medullary sheaths of nerves occurs in hens fed a diet of polished rice, attempts have been made to produce lesions of the nervous system experimentally by deficient diets. The earliest studies were concerned largely with deficiency of the antineuritic vitamin, B1, but in recent years vitamin A and the B2 complex have received attention. These investigations were in the main handicapped by inadequate information regarding the vitamins and by… Show more
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