Sensory nerves are frequently involved in the spectrum of fisher syndrome

Shahrizaila, Nortina; Goh, Khean Jin; Kokubun, Norito; Tan, Ai Huey; Tan, Cheng Yin; Yuki, Nobuhiro

doi:10.1002/mus.23973

Cited by 21 publications

(16 citation statements)

References 34 publications

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“…In contrast, NCS of MFS patients demonstrated either a normal (27%) or equivocal (49%) study. Previous studies have suggested that sensory neuropathy predominates in MFS 30,36 . The existing electrodiagnostic criteria rely on specific features of the motor nerves whereas pure sensory neuropathy would be classified as equivocal.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Guillain‐Barré syndrome and validation of the Brighton criteria in Malaysia

Tan

Razali

Goh

et al. 2020

J Peripheral Nervous Sys

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We aimed to evaluate the key diagnostic features of Guillain‐Barré syndrome (GBS) in Malaysian patients and validate the Brighton criteria. This was a retrospective study of patients presenting with GBS and Miller Fisher syndrome (MFS) between 2010 and 2019. The sensitivity of the Brighton criteria was evaluated. A total of 128 patients (95 GBS, 33 MFS) were included. In the GBS cohort, 92 (97%) patients presented with symmetrical limb weakness. Reflexes were depressed or absent in 90 (95%) patients. Almost all patients (94, 99%) followed a monophasic disease course, with 5 (5%) patients experiencing treatment‐related fluctuations. Cerebrospinal fluid (CSF) albuminocytological dissociation was seen in 62/84 (73%) patients. Nerve conduction study (NCS) revealed neuropathy in 90/94 (96%) patients. In GBS patients with complete dataset (84), 56 (67%) patients reached level 1 of the Brighton criteria, 21 (25%) reached level 2, 3 (4%) reached level 3, and 4 (5%) reached level 4. In MFS, the clinical triad was present in 25 (76%) patients. All patients had a monophasic course. CSF albuminocytological dissociation was present in 10/25 (40%) patients. NCS was normal or showed sensory neuropathy in 25/33 (76%) patients. In MFS patients with complete dataset (25), 5 (20%) patients reached level 1 of the Brighton criteria, 14 (56%) reached level 2, 2 (8%) reached level 3, and 4 (16%) reached level 4. Inclusion of antiganglioside antibodies improved the sensitivity of the Brighton criteria in both cohorts. In the Malaysian cohort, the Brighton criteria showed a moderate to high sensitivity in reaching the highest diagnostic certainty of GBS, but the sensitivity was lower in MFS.

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Section: Discussionmentioning

confidence: 99%

Diagnosis of Guillain‐Barré syndrome and validation of the Brighton criteria in Malaysia

Tan

Razali

Goh

et al. 2020

J Peripheral Nervous Sys

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“…NCS were performed using standardized techniques, as described elsewhere. [14][15][16] Proposed Electrodiagnostic Criteria for ERCF. Table 1 shows the proposed criteria for the presence of ERCF on serial NCS.…”

Section: Patientsmentioning

confidence: 99%

Electrodiagnosis of reversible conduction failure in Guillain–Barré syndrome

et al. 2017

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“…However, these patients may be at risk of developing Serial nerve conduction studies have demonstrated that the pathology of MFS is not demyelination, but axonal injury. 15 Immunological studies have shown that some patients develop MFS after Campylobacter jejuni infection, including those with GBS/MFS overlap. 16,17 These findings suggest that AMAN and MFS are part of the same spectrum of disease.…”

Section: Discussionmentioning

confidence: 99%