Sensory Inputs Stimulate Progenitor Cell Proliferation in an Adult Insect Brain

Scotto-Lomassese, Sophie; Strambi, Colette; Aouane, Aı̈cha; Strambi, Alain; Cayre, Myriam

doi:10.1016/s0960-9822(02)00889-8

Cited by 36 publications

(31 citation statements)

References 36 publications

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“…Increased KC branching is implicated in the experience-driven expansion of the calyx in forager honeybees (Farris et al 2001;Ismail et al 2006). In crickets, social enrichment, olfactory stimuli and visual stimuli all promote adult KC neurogenesis (Scotto-Lomassese et al 2002). The effect of grouprearing on KC neurogenesis has not yet been investigated in locusts, where KC neurogenesis shuts down in adults.…”

Section: Discussionmentioning

confidence: 99%

Gregarious desert locusts have substantially larger brains with altered proportions compared with the solitarious phase

2010

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The behavioural demands of group living and foraging have been implicated in both evolutionary and plastic changes in brain size. Desert locusts show extreme phenotypic plasticity, allowing brain morphology to be related to very different lifestyles in one species. At low population densities, locusts occur in a solitarious phase that avoids other locusts and is cryptic in appearance and behaviour. Crowding triggers the transformation into the highly active gregarious phase, which aggregates into dense migratory swarms. We found that the brains of gregarious locusts have very different proportions and are also 30 per cent larger overall than in solitarious locusts. To address whether brain proportions change with size through nonlinear scaling (allometry), we conducted the first comprehensive major axis regression analysis of scaling relations in an insect brain. This revealed that phase differences in brain proportions arise from a combination of allometric effects and deviations from the allometric expectation (grade shifts). In consequence, gregarious locusts had a larger midbrain : optic lobe ratio, a larger central complex and a 50 per cent larger ratio of the olfactory primary calyx to the first olfactory neuropile. Solitarious locusts invest more in low-level sensory processing, having disproportionally larger primary visual and olfactory neuropiles, possibly to gain sensitivity. The larger brains of gregarious locusts prioritize higher integration, which may support the behavioural demands of generalist foraging and living in dense and highly mobile swarms dominated by intense intraspecific competition.

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Section: Discussionmentioning

confidence: 99%

Gregarious desert locusts have substantially larger brains with altered proportions compared with the solitarious phase

2010

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“…Amputation of antennules in the adult shore crab reduces the rate of proliferation of neuronal precursor cells and impacts the survival of newly formed cells in the olfactory lobes (Hansen and Schmidt, 2001). In crickets, unilateral olfactory deprivation inhibits central neurogenesis, when performed with visual deprivation (Scotto-Lomassese et al, 2002). Olfactory axotomy increases cell genesis in the subventricular zone, rostral migratory stream, and olfactory bulb (Mandairon et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Peripheral sensory deafferentation affects olfactory bulb neurogenesis in zebrafish

Villanueva

Byrd-Jacobs

2009

Brain Research

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The potential effects of removal of olfactory input on adult neurogenesis in the olfactory bulb were examined. Olfactory organs of adult zebrafish were permanently and completely ablated by cautery and animals were exposed to bromodeoxyuridine then examined following short (4 hour) or long (3 week) survival periods. Short survival times allowed analysis of cell proliferation in the olfactory bulb. Long survival times permitted investigation of survival of adult-formed cells. Deafferentation did not immediately affect the dividing cells in the bulb but did affect the number of adult-formed cells, some of which expressed a neuronal marker, present in the bulb three weeks later. Thus, afferent removal influenced the fate of newly formed cells by impacting subsequent divisions, maturation, or survival of those cells. One week of deafferentation altered the pattern of cell genesis, with a significant increase in the number of dividing cells located in the olfactory bulb and also in the ventral telencephalic proliferation zone. Sham surgery did not impact either proliferation or survival of adultformed cells in the olfactory bulb, suggesting that the deafferentation effect is specific. Thus, afferent innervation is necessary for normal cell proliferation and maintenance of the olfactory bulb in adult zebrafish.

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“…Structural plasticity correlated with physiological and behavioral demands and/or age-dependent changes has also been documented for diverse neuropils in insect brains, including the antennal lobe neuropil, the primary chemosensory neuropil linked to the MBs by iACT-PNs (Technau, 1984;Withers et al, 1993;Heisenberg et al, 1995;Heisenberg, 1998;Meinertzhagen, 2001;Brown et Scotto-Lomassese et al, 2002;Devaud et al, 2003). A recent Golgi study by Farris et al (2001) in the honey bee showed experience-and age-related changes in KC dendritic trees.…”

Section: F-actin and Structural Plasticity Of The Mushroom Bodiesmentioning

confidence: 96%

F‐actin at identified synapses in the mushroom body neuropil of the insect brain

Frambach

Rößler

Winkler

et al. 2004

J of Comparative Neurology

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The distribution of f-actin stained by fluorescent phalloidin was investigated in the brain of several insect species, with a special focus on the mushroom body. For localizing f-actin in identified neurons and at synapses, additional staining with fluorescent dextrans and anti-synapsin I immunostaining was employed. Intense f-actin staining was consistently found in synaptic complexes of the mushroom body calyces (calycal microglomeruli [MG]). These MG contain a central core of presynaptic boutons, predominantly belonging to deutocerebral cholinergic excitatory projection neurons, which are surrounded by a shell of numerous Kenyon cell (KC) dendritic tips. In the cricket Gryllus bimaculatus, high-resolution confocal laser scanning imaging revealed colocalization of f-actin with KC dendritic spine parts within MG. Although presynaptic boutons appear to be mainly devoid of f-actin-phalloidin fluorescence, there appears to be an accumulation of f-actin in KC dendritic spines synaptically contacting the boutons. Electron microscopy of boutons and dextran-stained KC dendrites revealed their pre- and postsynaptic sites, with KCs being strictly postsynaptic elements. Their subsynaptic membrane appositions are considered to be associated with f-actin. Focal accumulation of f-actin in the dendritic tips of KCs was found to be a general feature of MG, with either spheroidal or indented boutons of different sizes, as encountered in the mushroom bodies of the cricket, honey bee, ant, and fruit fly. The structural similarities of calycal MG and f-actin accumulation in KC dendrites with cerebellar microglomeruli are considered comparatively. The accumulation of f-actin in KC dendrites is discussed in view of mushroom body plasticity and its potential role in learning and memory formation.

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Sensory Inputs Stimulate Progenitor Cell Proliferation in an Adult Insect Brain

Cited by 36 publications

References 36 publications

Gregarious desert locusts have substantially larger brains with altered proportions compared with the solitarious phase

Gregarious desert locusts have substantially larger brains with altered proportions compared with the solitarious phase

Peripheral sensory deafferentation affects olfactory bulb neurogenesis in zebrafish

F‐actin at identified synapses in the mushroom body neuropil of the insect brain

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