Sensory exam with a quantitative tuning fork

Pestronk, Alan; Florence, Julaine; Levine, Todd; Al‐Lozi, Muhammad; Lopate, Glenn; Miller, Timothy M.; Ramneantu, I.; Waheed, Waqar; Stambuk, M.

doi:10.1212/01.wnl.0000106939.41855.36

Cited by 108 publications

(70 citation statements)

References 12 publications

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“…ability to feel 0-131 microns). Some tuning forks can provide a quantitative measure of vibration threshold that has been shown to correlate with the SNAP amplitude [23]. Work by Oyer and colleagues suggests that categorizing tuning fork thresholds as 10 seconds or less can detect significant impairment in diabetic adults (ages of participants not reported) who exhibit normal 10-g monofilament detection [48].…”

Section: Discussionmentioning

confidence: 99%

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Mobility-Related Consequences of Reduced Lower-Extremity Peripheral Nerve Function with Age: A Systematic Review

Ward¹,

Caserotti²,

Cauley³

et al. 2016

Aging and disease

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The objective of this study is to systematically review the relationship between lower-extremity peripheral nerve function and mobility in older adults. The National Library of Medicine (PubMed) was searched on March 23, 2015 with no limits on publication dates. One reviewer selected original research studies of older adults (≥65 years) that assessed the relationship between lower-extremity peripheral nerve function and mobility-related outcomes. Participants, study design and methods of assessing peripheral nerve impairment were evaluated and results were reported and synthesized. Eight articles were identified, including 6 cross-sectional and 2 longitudinal studies. These articles investigated 6 elderly cohorts (4 from the U.S. and 2 from Italy): 3 community-dwelling (including 1 with only disabled women and 1 without mobility limitations at baseline), 1 with both community-dwelling and institutionalized residents, 1 from a range of residential locations, and 1 of patients with peripheral arterial disease. Mean ages ranged from 71-82 years. Nerve function was assessed by vibration threshold (n=2); sensory measures and clinical signs and symptoms of neuropathy (n=2); motor nerve conduction (n=1); and a combination of both sensory measures and motor nerve conduction (n=3). Each study found that worse peripheral nerve function was related to poor mobility, although relationships varied based on the nerve function measure and mobility domain assessed. Six studies found that the association between nerve function and mobility persisted despite adjustment for diabetes. Evidence suggests that peripheral nerve function impairment at various levels of severity is related to poor mobility independent of diabetes. Relationships varied depending on peripheral nerve measure, which may be particularly important when investigating specific biological mechanisms. Future research needs to identify risk factors for peripheral nerve decline beyond diabetes, especially those common in late-life and modifiable.Interventions to preserve nerve function should be investigated with regard to their effect on postponing or preventing disability in older adults.

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Section: Discussionmentioning

confidence: 99%

“…The vibration is increased until the participant reports feeling it. Another method is a quantitative tuning fork, which involves adjusting calibrated weights on the two arms of the fork, to change the vibration from a scale of 0 to 8 [23]. With this method, the participant reports when they no longer feel the vibration.…”

Section: Vibration Detection Thresholdmentioning

confidence: 99%

Mobility-Related Consequences of Reduced Lower-Extremity Peripheral Nerve Function with Age: A Systematic Review

Ward¹,

Caserotti²,

Cauley³

et al. 2016

Aging and disease

View full text Add to dashboard Cite

show abstract

“…Besides personal characteristics, information about the cause, location and severity of the SCI lesion was provided. Sensory vibration threshold was tested using a ReidelSeiffer tuning fork [11,12]. Strength of the foot dorsal flexors was tested using a torque measurement device (see Methods), while walking capacity was tested using 10 m walk tests [13] at preferred and maximum speed, as well as the revised version of the Walking Index for Spinal Cord Injury (WISCI II; [14]).…”

Section: Methods J Subjectsmentioning

confidence: 99%

The amplitude of lower leg motor evoked potentials is a reliable measure when controlled for torque and motor task

et al. 2007

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“…However, not all oncologists are comfortable with neuroexamination. Clinical examination is rapid, cheap, reproducible, easy to learn and predictive of neurophysiological alterations [15][16][17].…”

Section: Diagnosismentioning

confidence: 99%

Chemotherapy-induced peripheral neuropathy: clinical features, diagnosis, prevention and treatment strategies

et al. 2010

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Chemotherapy-induced peripheral neuropathy (CIN) is a common toxicity of anticancer treatment and its incidence is growing. It significantly affects quality of life and is a dose-limiting factor that interferes with treatment. Its diagnosis can be established in clinical terms but some complementary tests can help when the diagnosis is difficult. There is still no proven method to prevent it that has become a standard of care in spite of the huge amount of investigation carried out in recent years. There are promising strategies that could help reduce the burden of this complication. This review will suggest an approach to the diagnosis of these disorders and provide an update on new therapies.

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Sensory exam with a quantitative tuning fork

Cited by 108 publications

References 12 publications

Mobility-Related Consequences of Reduced Lower-Extremity Peripheral Nerve Function with Age: A Systematic Review

Mobility-Related Consequences of Reduced Lower-Extremity Peripheral Nerve Function with Age: A Systematic Review

The amplitude of lower leg motor evoked potentials is a reliable measure when controlled for torque and motor task

Chemotherapy-induced peripheral neuropathy: clinical features, diagnosis, prevention and treatment strategies

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