Multimodal sensing and data processing have become a common approach in modern assisted living systems. This is widely justified by the complementary properties of sensors based on different sensing paradigms. However, all previous proposals assume data fusion to be made based on fixed criteria. We proved that particular sensors show different performance depending on the subject’s activity and consequently present the concept of an adaptive sensor’s contribution. In the proposed prototype architecture, the sensor information is first unified and then modulated to prefer the most reliable sensors. We also take into consideration the dynamics of the subject’s behavior and propose two algorithms for the adaptation of sensors’ contribution, and discuss their advantages and limitations based on case studies.