Sensorineural hearing loss in chronic suppurative otitis media with and without cholesteatoma

Azevedo, Alexandre Fernandes de; Pinto, Daniele Cristine Gomes; Souza, Nicodemos José Alves de; Greco, Dirceu Bartolomeu; Gonçalves, Denise Utsch

doi:10.1016/s1808-8694(15)30128-2

Cited by 53 publications

(79 citation statements)

References 15 publications

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“…Moreover, when we analyzed the effect of the patients' age on the degree of SNHL in the diseased ears, there was still no significant correlation. On the contrary, other workers had found that increasing age was a risk factor in the evolution of SNHL in patients with CSOM [6,15]. The discrepancies in the study populations with respect to the patients' ages could possibly be responsible for the differences in our findings.…”

Section: Discussioncontrasting

confidence: 83%

“…Likewise, previous authors had also arrived at the same conclusion [6,7]. Moreover, when we analyzed the effect of the patients' age on the degree of SNHL in the diseased ears, there was still no significant correlation.…”

Section: Discussionsupporting

confidence: 63%

“…In contrast, de Azevedo et al [6] found no strong evidence of the effect of the disease on BC thresholds at any frequency.…”

Section: Discussionmentioning

confidence: 86%

“…Bone conduction (BC) thresholds for the frequencies of 0.5, 1.0, 2.0, and 4.0 kHz were considered for this study. In order to increase the sensitivity of the study, we defined SNHL as an intensity of 30 dB or more for the BC thresholds in two or more frequencies (those with significant cochlear damage) [6]. The main outcome measures were the BC threshold averages for the frequencies 0.5, 1.0, 2.0, and 4.0 kHz; and with comparison between the control and diseased ears.…”

Section: Discussionmentioning

confidence: 99%

“…However, the relationship between sensorineural hearing loss (SNHL) and CSOM remains a controversial issue. For instance, some workers have consistently reported the presence of SNHL in patients with this condition [6][7][8][9][10]. On the contrary, some investigators have reiterated the fact that little or no such relationship exist [11,12].…”

Section: Introductionmentioning

confidence: 99%

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Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Kolo

Salisu

Yaro

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Even though there are other complications of chronic suppurative otitis media, the aspect of hearing loss is often studied. Nevertheless, the occurrence of sensorineural hearing loss in patients with this disease is still controversial. This study aim (1) to assess the association between sensorineural hearing loss and chronic suppurative otitis media, (2) to investigate some clinical factors that might affect the sensorineural component in patients with this disease. This was a retrospective analysis of the clinical records and pure tone audiograms of patients with chronic suppurative otitis media in a Nigerian Tertiary Health Institution from January 2003 to December 2008. Sixty-nine patients with a mean age of 28.93 years; standard deviation of 18.593 were studied. They had an age range of 4-73 years. The duration of otorrhea ranged from 2 months to 20 years; with a mean of 6.11 years (standard deviation of 6.393). The mean bone conduction threshold in the diseased ear was 39.07 dB (standard deviation of 12.028), and 10.26 dB (standard deviation of 2.620) in the control ear (P \ 0.05). The mean bone conduction threshold differences between the diseased and control ears range from 21.69 to 34.52 dB across the frequencies 0.5, 1.0, 2.0, and 4.0 kHz. These differences tended to increase with increasing frequency and were all significant (P \ 0.05). In the diseased ears, there were no significant correlation between the age, duration of otorrhea, and the degree of SNHL (r = 0.186, P [ 0.05; r = 0.190, P [ 0.05 respectively). Patients with chronic suppurative otitis media had a significant degree of sensorineural hearing loss in this study. The higher frequencies were more affected; however, the patient's age and duration of otorrhea seem not to have any correlation with the degree of sensorineural hearing loss.

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Section: Discussioncontrasting

confidence: 83%

Section: Discussionsupporting

confidence: 63%

“…In contrast, de Azevedo et al [6] found no strong evidence of the effect of the disease on BC thresholds at any frequency.…”

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Kolo

Salisu

Yaro

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Gram‐negative Bacteria are Associated With Sensorineural Hearing Loss in Chronic Otitis Media

Lou,

He,

Cui

et al. 2024

The Laryngoscope

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ObjectChronic otitis media (COM) is an inflammatory disease that commonly presents with otorrhea and hearing loss. Bacteria‐induced inflammation can cause inner ear damage, leading to sensorineural hearing loss (SNHL). This study aimed to compare the prevalence and severity of SNHL in patients with gram‐negative versus gram‐positive cultures and examine associations between the concentrations of circulating monocytes and neutrophils with bacteria species and SNHL.MethodsThis was a retrospective study. Cholesteatoma or chronic suppurative otitis media patients with otorrhea were enrolled. Middle ear secretions were collected using sterile swabs under an otoscope, and sent for bacterial detection within 30 min. Pure tone audiometry and circulating leukocyte counts were recorded and analyzed in patients infected with different pathogens. Logistic regression analysis was used to identify the risk factors associated with SNHL.ResultsA total of 137 patients were enrolled, including 45 patients infected with gram‐negative bacteria, 41 with gram‐positive bacteria, 20 with polymicrobial infection, and 31 with no bacterial growth. Logistic regression analysis showed that bacterial culture positive infections (OR = 7.265, 95% CI 2.219–23.786, p = 0.001) were an independent risk factor for SNHL. Patients with gram‐negative bacteria had higher risks of SNHL (p < 0.0001) and more severe hearing loss (p = 0.005) than those with gram‐positive bacteria. COM patients infected with gram‐negative bacteria showed an increase in circulating monocytes, which correlated with the occurrence of SNHL (p = 0.0343).ConclusionGram‐negative bacteria are associated with elevated circulating monocyte counts and have a higher risk of severe SNHL.Level of Evidence4 Laryngoscope, 2024

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Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

Sharma

Manjari

Salaria

2011

Indian J Otolaryngol Head Neck Surg

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Chronic mucosal diseases of middle ear cleft or chronic suppurative otitis media has been traditionally defined as a chronic inflammation of the middle ear and mastoid usually associated with perforation of the tympanic membrane and otorrhoea. Understanding the pathology and pathogenesis of chronic suppurative otitis media is important in predicting the management, prognosis and sequelae of the disease. The present prospective study was conducted to evaluate the clinical, intraoperative and histopathological changes in middle ear cleft. 100 patients diagnosed with CSOM who underwent surgery were taken. The mucosa and granulation tissue was removed along with ossicles wherever indicated and sent for histopathological examination. On clinical examination, 72 cases were found to be of tubotympanic type and 28 cases of atticoantral variety. However, intraoperatively, of the tubotympanic cases 8 were found to be of unsafe type which was also proven histologically. Stratified squamous epithelium was revealed in most of the cases accompanied by changes in the submucosa. Ossicular chain was involved in 40 cases with incus being the commonest bone to be eroded.

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Sensorineural hearing loss in chronic suppurative otitis media with and without cholesteatoma

Cited by 53 publications

References 15 publications

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Sensorineural Hearing Loss in Patients with Chronic Suppurative Otitis Media

Gram‐negative Bacteria are Associated With Sensorineural Hearing Loss in Chronic Otitis Media

Middle Ear Cleft in Chronic Otitis Media: A Clinicohistopathological Study

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