Sensorineural hearing loss associated with psoriatic arthritis

Introduction Several authors have demonstrated the relationship between sudden sensorineural hearing loss (SNHL) and systemic autoimmune diseases (SAD). Immune-mediated SNHL can rarely present as unilateral sudden SNHL and manifests itself in the contralateral ear only after years. It presents clinical relevance for being one of the few SNHL that may be reversible given that early and appropriate treatment is applied. Objective The objective of this study is to describe the clinical presentations and audiological findings from patients with idiopathic sudden SNHL and SAD associated with a probable diagnosis of immune-mediated SNHL. Furthermore, we strive to estimate the prevalence of SAD in patients with sudden SNHL. Methods This is an observational retrospective cohort. We have selected and studied patients with SAD. Revision of available literature on scientific repositories. Results We evaluated 339 patients with sudden SNHL. Among them, 13 (3.83%) patients suffered from SAD. Three patients had bilateral involvement, a total of 16 ears. We evaluate and describe various clinical, epidemiological, and audiological aspects of this sample. Conclusion In our sample of patients with sudden SNHL, the prevalence of SAD was found relevant. The majority had tinnitus and dizziness concomitant hearing loss, unilateral involvement and had experienced profound hearing loss at the time of the installation. In spite of instituted treatment, most cases showed no improvement in audiometric thresholds. Apparently, patients with sudden SNHL and SAD have a more severe initial impairment, higher percentage of bilateral, lower response to treatment, and worse prognosis than patients with sudden SNHL of unknown etiology.

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“…We found little evidence in the literature showing a possible link between this disease and sudden SNHL. 40 …”

Section: Discussionmentioning

confidence: 99%

Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases

Rossini

Penido

Munhoz

et al. 2016

Int Arch Otorhinolaryngol

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“…However, Yen et al ., in their study testing the hypothesis that patients with psoriasis have a risk of developing SNHL, found a 1.51 times higher incidence after 6 years of follow‐up than in the HC group . There are also a few case reports about sensorineural hearing loss associated with psoriatic arthritis …”

Section: Reportmentioning

confidence: 99%

Investigation of high‐frequency hearing loss and outer hair cell function of the cochlea in patients with psoriasis: a case–control study

Vir¹,

Sharma²,

Mahajan

et al. 2018

Clin Exp Dermatol

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Summary The inner ear can be the target of autoimmune attacks, and sensorineural hearing loss can occur as a complication in various non‐organ‐specific autoimmune diseases. The aim of this study was to compare cochlear functions and hearing evaluation in patients with psoriasis and controls. In total, 29 patients with psoriasis and 30 healthy controls (HCs) were included in the study. Pure‐tone audiometry at 250, 500, 1000, 2000, 4000, 8000, 10 000, 12 000, 14 000 and 16 000 Hz was performed for patients as HCs, as were immittance measures including tympanometry, acoustic reflex and otoacoustic emission testing. There were statistically significant (P < 0.05) differences between patients and HCs for pure‐tone thresholds at high frequencies, and for distortion product otoacoustic emission (DPOAE) responses and signal : noise ratio at all frequencies. In our study, based on DPOAE and audiological findings, there was damage to the outer hair cells of the cochlea, resulting in high‐frequency hearing loss in patients with psoriasis.

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“…[12] Since then several studies of autoimmune involvement of facial nerve involvement and inner ear have been published. [13] Reported rates of facial nerve involvement and inner ear disease in NBD are (15-40%). NeuroBehchets disease is a rare disease and diagnosis can be reached by taking a careful history.…”

Section: Discussionmentioning

confidence: 99%