Sensitization Dermatitis to Carrots

Occupational allergic contact dermatitis from falcarinol

“…The cut surface of the carrot root gives the strongest patch test reactions (9). The dermatitis mainly affected our patient's non‐dominant hand because the patient held vegetables with this, while cutting them with her dominant hand, and the allergen was able to penetrate domestic rubber gloves (10).…”

“…The dermatitis mainly affected our patient's non‐dominant hand because the patient held vegetables with this, while cutting them with her dominant hand, and the allergen was able to penetrate domestic rubber gloves (10). Most patients with positive patch tests to carrot are able to tolerate eating it, though such vegetables eaten raw or cooked can cause cheilitis and perioral dermatitis (9), as well as glossal oedema (11) and anaphylaxis (12). However, this latter allergen could be a thermolabile protein (12) as, when the carrots were boiled, no symptoms appeared.…”

“…Cross‐sensitization may occur with other members of the Umbelliferae family such as parsley, celery and parsnip (9). A number of Araliaceae family plants, such as common ivy, Schefflera actinophylla (umbrella tree) and Schefflera arboricola (13), should be also avoided by falcarinol‐allergic patients (14).…”

Mode of Action of Psoralens

“…It has long been known that photosensitization dermatitis with residual pigmentation develojss in skin Avhich has come in contact Avith certain speeies of plants (Bellringer, 1949 ;Goldsmith aud Hellier, 1954 ;Klaber, 1942 ;Klauder and Kimich, 1956). Klaber (1942) suggested the term " phytophotodermatitis " to denote the reaction to sunlight of skin which has been in contact with such plants. The relation between the chemical components of these plants and the development of phytoj)hotodermatitis was established by Klauder (1956).…”

Actual Causes of Certain Occupational Dermatoses

“…In my first report,1 in 1943, it was observed that the specific causes fell into a number of main groups (shown in the Table) each with subdivisions that were discussed in the report. In subsequent reports 2,3,4 an additional number of cases of occupational dermatoses were added to the Submitted for publication Nov. 10,1961. [Stockh.]…”