Sensitivity of the Saline Load Test With and Without Methylene Blue Dye in the Diagnosis of Artificial Traumatic Knee Arthrotomies

Metzger, Paul; Carney, J.M.; Kuhn, Kevin; Booher, Kermit; Mazurek, Michael T.

doi:10.1097/bot.0b013e3182255167

Cited by 22 publications

(26 citation statements)

References 8 publications

(16 reference statements)

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“…The observed wide range of the knee volume (40-290 ml) explains the low sensitivity and specificity of the saline load test that is used to determine a traumatic capsule defect [9][10][11][12]. This problem limits the diagnostic value of the saline load test with reported cut-off values between 60 and 194 ml [9][10][11][12].…”

Section: Discussionmentioning

confidence: 92%

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The volume of the human knee joint

Matziolis

Roehner

Windisch

et al. 2015

Arch Orthop Trauma Surg

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Section: Discussionmentioning

confidence: 92%

“…This problem limits the diagnostic value of the saline load test with reported cut-off values between 60 and 194 ml [9][10][11][12].…”

Section: Discussionmentioning

confidence: 94%

The volume of the human knee joint

Matziolis

Roehner

Windisch

et al. 2015

Arch Orthop Trauma Surg

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“…These are CT scan,2 saline load tests (SLTs)3–6 and SLT with methylene blue 7. CT scan sensitivity and specificity for detecting TA with intra-articular air has been reported at 100% in other joints and has largely replaced the SLT 3.…”

Section: Introductionmentioning

confidence: 99%

Traumatic elbow arthrotomy after motorcycle accident not evident on CT

Bunyasaranand¹,

Foeger

Ryan

2017

BMJ Case Reports

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An 84-year-old man sustained a motorcycle accident resulting in a left elbow laceration. Orthopaedics was consulted to rule out traumatic arthrotomy. Radiographs and CT of the left elbow showed no acute osseous abnormalities and no evidence of traumatic arthrotomy. The wound was irrigated, dressed and splinted. On follow-up, the patient reported that he had been given clindamycin on a return visit to the emergency department for increased drainage. On inspection, the patient's wound was found sutured and draining purulent fluid. The patient persistently had no pain on axial loading or range of motion since his injury and no evidence of intra-articular air on initial CT. However, given the mechanism of injury, irrigation and debridement (I&D) in the operating room was immediately performed revealing purulent joint fluid and a traumatic arthrotomy. I&D was carried out for the second time in the joint. After an extended hospital stay and antibiotics, the infection resolved.

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“…Therefore, a new photosensitizer is needed for treatment of HS. Methylene blue (MB) is a phenothiazonium compound that has been approved by the US Food and Drug Authority for the treatment of methaemoglobinaemia and urinary tract infections and in some diagnostic tests …”

Section: Introductionmentioning

confidence: 99%

“…Methylene blue (MB) is a phenothiazonium compound that has been approved by the US Food and Drug Authority for the treatment of methaemoglobinaemia and urinary tract infections and in some diagnostic tests. 11,12 There are a number of drug delivery systems available to increase drug delivery to the target organ. Niosomes are non-ionic surfactant-based liposomes, and as a novel drug delivery system, can play an important role in improving the topical delivery of photosensitizers by enhancing their dermal localization and consequently optimizing efficacy of the therapeutic agents.…”

Section: Introductionmentioning

confidence: 99%