Sensitivity of the resting sodium conductivity of leech retzius nerve cells to tetrodotoxin

Effects of Oxidative Stress on the Electrophysiological Function of Neuronal Membranes

“…The Retzius cells, are the largest neurons (40-60 µm in diameter) situated on the ventral side of the ganglia. It is well known that the resting potential of Retzius nerve cells of medical and horse leeches are lower than in other neurons (Hagiwara & Morita, 1962;Beleslin, 1985). Theoretically, this can be due to the low resting potassium permeability or the high membrane permeability to sodium.…”

“…The Retzius cell is spontaneously active and responds to depolarization with an increased firing rate proportional to the depolarization (Lent, 1977). In leech Retzius nerve cells three classes of K + channels (fast, slow calcium-activated and late voltage-regulated) have been identified (Beleslin et al, 1982;Beleslin, 1985). To change the solution, the chamber was flushed continuously with a volume of fluid at least five times that of the chamber volume.…”

Oxidative Stress and Diseases

“…The Retzius cells, are the largest neurons µm in diameter) situated on the ventral side of the ganglia. It is well known that the resting potential of Retzius nerve cells of medical and horse leeches are lower than in other neurons (Hagiwara & Morita, 1962;Beleslin, 1985). Theoretically, this can be due to the low resting potassium permeability or the high membrane permeability to sodium.…”

“…The Retzius cell is spontaneously active and responds to depolarization with an increased firing rate proportional to the depolarization (Lent, 1977). In leech Retzius nerve cells three classes of K + channels (fast, slow calcium-activated and late voltage-regulated) have been identified (Beleslin et al, 1982;Beleslin, 1985). To change the solution, the chamber was flushed continuously with a volume of fluid at least five times that of the chamber volume.…”

Electrophysiological Effect of β‐N‐Methylamino‐L‐Alanine on Retzius Nerve Cells of the Leech Haemopis sanguisuga

“…The leeches were dissected as previously described 4. Intracellular recordings were made using glass tube microelectrodes filled with 3 M KCl, with resistance of 15–25 MΩ.…”