2019
DOI: 10.3389/fmicb.2019.02342
|View full text |Cite
|
Sign up to set email alerts
|

Sensitivity of Commercially Available Influenza Rapid Diagnostic Tests in the 2018–2019 Influenza Season

Abstract: Epidemics of seasonal influenza caused by H1N1pdm09, H3N2, and type B viruses occur throughout the world. Sporadic human H5 and H7N9 virus infections are also reported in particular regions. To treat influenza patients effectively with antivirals, sensitive and broad-reactive influenza rapid diagnostic tests (IRDTs) are required. Here, we tested the sensitivity of 23 IRDTs during the 2018–2019 influenza season for their ability to detect H1N1pdm09, H3N2, H5N1, H5N6, H7N9, and Victoria- and Yamagata-lineage typ… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2020
2020
2023
2023

Publication Types

Select...
5

Relationship

1
4

Authors

Journals

citations
Cited by 5 publications
(3 citation statements)
references
References 23 publications
0
3
0
Order By: Relevance
“…However, RATs with superior sensitivity are useful for rapid diagnosis especially in limited resource settings where RT-qPCR is hard to perform, because they allow for immediate isolation of individuals shedding a large amount of virus. The sensitivity of influenza RATs has improved over time since their inception [23][24][25][26]; therefore, we anticipate that COVID-19 RATs that are more sensitive will be developed in the near future to support the control of COVID-19 and to help initiate treatment early after onset.…”
Section: Discussionmentioning
confidence: 99%
“…However, RATs with superior sensitivity are useful for rapid diagnosis especially in limited resource settings where RT-qPCR is hard to perform, because they allow for immediate isolation of individuals shedding a large amount of virus. The sensitivity of influenza RATs has improved over time since their inception [23][24][25][26]; therefore, we anticipate that COVID-19 RATs that are more sensitive will be developed in the near future to support the control of COVID-19 and to help initiate treatment early after onset.…”
Section: Discussionmentioning
confidence: 99%
“…For the diagnosis of influenza, a variety of IRDTs, which are easy, rapid, and low cost, are currently widely used in Japan, and likely the most commonly-used influenza confirmatory tests captured in our study. The sensitivity of IRDTs for seasonal influenza B viruses is lower or similar compared to that of seasonal influenza A viruses [32]. The reported sensitivities of IRDTs for influenza viruses in general ranges between 10%-80%, with lower sensitivity observed among older adults and in those with underlying conditions [14,[33][34][35].…”
Section: Plos Onementioning
confidence: 99%
“…[9] LFIA, typically used in rapid influenza diagnostic tests (rapid kits), takes advantage of the localized surface plasmon resonance (LSPR) properties of gold nanoparticles (GNPs) in the detection of viruses, leading to rapid results via simple analysis [9] and an extremely high detection limit as compared to other methods. [10,11] However, all three methods detect viral components only (proteins or RNA) and the selective detection of infectious virions (intact, active viruses) remains challenging. For influenza viruses to possess infectivity, they must be intact, whole virions that can fuse with host cells and replicate their viral genomes.…”
Section: Introductionmentioning
confidence: 99%