Sensitivity of a Standard Host Resistance Assay Using Streptococcus agalactiae for Assessing Exposure to Immunotoxicants in Wild Cotton Rats ( Sigmodon hispidus )
Abstract:Resident small mammals have been used for in situ biomonitoring of contaminated waste sites containing suspected immunotoxicants. Host resistance assays, which involve challenging animals with an actual pathogen, allow for testing of overall immune system function in animals. Because such assays have not been evaluated for use with wild rodent species, it was our objective to assess the efficacy of Streptococcus agalactiae as a pathogenic model for use in a host resistance assay for detecting alterations in im… Show more
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