Sensitivity and specificity of ultrasonographic features of gout in intercritical and chronic phase

Das, Shyamashis; Ghosh, Alakendu; Ghosh, Parasar; Lahiri, Debasish; Sinhamahapatra, Pradyot; Basu, Kaushik

doi:10.1111/1756-185x.12928

Cited by 21 publications

(8 citation statements)

References 20 publications

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“…The most common joint involved was ankle, followed by the metatarsophalangeal joints. Previous studies also have shown a male preponderance with metatarsophalangeal joints, knee and ankle being the most common sites of involvement (15). Tubercular arthritis is among the commonest causes of infectious arthritis in endemic areas.…”

Section: Discussionmentioning

confidence: 99%

Infectious versus non-infectious causes of oligoarticular inflammatory arthritis: A prospective study from a tertiary care hospital in north India

Gupta

Chaudhry

Valappil

et al. 2019

DD&T

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Section: Discussionmentioning

confidence: 99%

Infectious versus non-infectious causes of oligoarticular inflammatory arthritis: A prospective study from a tertiary care hospital in north India

Gupta

Chaudhry

Valappil

et al. 2019

DD&T

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“…Other studies have also supported high specificity (90% range) for DCS [55][56][57]. However, in patients with gout for less than 2 years, sensitivity (50%) is lower than for patients with established disease ≥ 2 years duration (63%).…”

Section: Ultrasound Evaluation Of Crystalline Arthropathymentioning

confidence: 90%

Diagnostic advances in synovial fluid analysis and radiographic identification for crystalline arthritis

Zell¹,

Zhang²,

Fitzgerald³

2019

Current Opinion in Rheumatology

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Purpose of review: This review addresses diagnostic methods for crystalline arthritis including synovial fluid analysis, ultrasound and dual energy CT scan (DECT). Recent findings:There are new technologies on the horizon to improve the ease, sensitivity and specificity of synovial fluid analysis. Raman spectroscopy uses the spectral signature that results from a material's unique energy absorption and scatter for crystal identification. Lens-free microscopy directly images synovial fluid aspirate on to a complementary metal-oxide semiconductor (CMOS) chip, providing a high-resolution, wide field of view (~20 mm 2 ) image. Raman spectroscopy and lens-free microscopy may provide additional benefit over compensated polarized light microscopy (CPLM) synovial fluid analysis by quantifying crystal density in synovial fluid samples. Ultrasound and DECT have good sensitivity and specificity for the identification of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals. However, both have limitations in patients with recent onset gout and low urate burdens.Summary: New technologies promise improved methods for detection of MSU and CPP crystals. At this time, limitations of these technologies do not replace the need for synovial fluid aspiration for confirmation of crystal detection. None of these technologies address the often concomitant indication to rule out infectious arthritis.

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“…There are many practical advantages in the use of ultrasound for the evaluation of gout compared to the previously mentioned imaging modalities. These include ultrasound's ready availability at the bedside, low operational costs and time, real-time information for clinicians, and the ability to perform a rapid examination of multiple locations [22][23][24]. The increase of skilled clinician sonographers and of ultrasound equipment makes POCUS an ideal bedside tool for the assessment of the patient with crystal arthropathy.…”

Section: Ultrasound Features Of Goutmentioning

confidence: 99%

Images in Primary Care Medicine: Point-of-Care Ultrasound in Gout

Espejo¹,

Dearing²,

Ogle³

et al. 2021

Cureus

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Gout is the most common crystal arthropathy and is frequently diagnosed and managed by primary care physicians. Point-of-care ultrasound (POCUS) is a valuable tool to aid in the diagnosis of gout via the identification of the double contour sign, aggregates of crystals, tophi, and erosions. In addition, POCUS can aid in the management of gout by recognizing early signs of gout, monitoring the effectiveness of uratelowering therapy, and guiding aspiration and corticosteroid injection.

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Sensitivity and specificity of ultrasonographic features of gout in intercritical and chronic phase

Abstract: MSUS is useful for diagnosis of gout in intercritical or chronic stages, especially in patients with persistently high SUA level.

Cited by 21 publications

References 20 publications

Infectious versus non-infectious causes of oligoarticular inflammatory arthritis: A prospective study from a tertiary care hospital in north India

Infectious versus non-infectious causes of oligoarticular inflammatory arthritis: A prospective study from a tertiary care hospital in north India

Diagnostic advances in synovial fluid analysis and radiographic identification for crystalline arthritis

Images in Primary Care Medicine: Point-of-Care Ultrasound in Gout

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