Sensitive to the effects of environmental factors miR-638 and common diseases

Abstract

The review provides information on environmental factors affecting the level of miR-638 in humans, potential target genes of this micro-RNA (according to TargetScanHuman), diseases and metabolic pathways which potentially regulated miR-638, as well as clinical and experimental data confirming the involvement of miR-638 in the developing a wide range of multifactorial diseases. The data presented in the review expand the understanding of the pathogenesis of various diseases of a multifactorial nature and determine new strategies for studying gene-environment interactions that are important for the formation of health.