Sensitive microRNA detection based on bimetallic label photothermal lateral flow locked nucleic acid biosensor with smartphone readout

Unlocking the potential of perovskite-based nanomaterials for revolutionary smartphone-based sensor applications

“…5,[13][14][15][16] The success of these sophisticated sensors is fundamentally dependent on the innovative materials from which they are constructed. [17][18][19] A variety of nanomaterials have demonstrated potential in this arena: graphene, with its extraordinary electrical conductivity and surface area; [20][21][22] goldbased nanomaterials, [23][24][25][26] revered for their distinctive plasmonic properties; and polymer dots, 27,28 quantum dots, 29,30 which may integrate seamlessly with existing semiconductor frameworks. Yet, within this innovative spectrum, Perovskite-based nanomaterials offer unmatched benefits for the evolution of smartphone-integrated sensors.…”

Smartphone-Based Photothermal Lateral Flow Immunoassay Using Rhenium Diselenide Nanosheet

“…Gold composite nanomaterials such as Au@Pd, black phosphorescence@Au, Fe 3 O 4 @Au, and Pd@Au were designed as photothermal labels in LFIAs for the detection of exosomes, antibiotics, mycotoxin, and bacteria. 31 − 34 However, GNP suffers from low photothermal conversion efficiency and photothermal stability, limiting its further applications. It is reported that carbon nanomaterials, such as carbon nanotube (CNT) and graphene oxide (GO), have good photothermal properties and can be utilized to develop photothermal sensing strategies in LFIAs.…”

“…Based on the thermal signal of gold nanoparticle (GNP), the detection sensitivity of commercial LFIA for influenza A, malaria, and Clostridium difficile has been improved. − Recently, many nanomaterials with good photothermal properties have been used to improve the analytical performance of photothermal LFIAs. Gold composite nanomaterials such as Au@Pd, black phosphorescence@Au, Fe 3 O 4 @Au, and Pd@Au were designed as photothermal labels in LFIAs for the detection of exosomes, antibiotics, mycotoxin, and bacteria. − However, GNP suffers from low photothermal conversion efficiency and photothermal stability, limiting its further applications. It is reported that carbon nanomaterials, such as carbon nanotube (CNT) and graphene oxide (GO), have good photothermal properties and can be utilized to develop photothermal sensing strategies in LFIAs. , Two-dimensional transition metal sulfide nanomaterials with high specific surface area and high photothermal effect have demonstrated great potential in various rapid detection methods. , Based on MoS 2 and WS 2 , photothermal LFIAs were developed for the detection of Salmonella typhimurium and clenbuterol. , The ReSe 2 is a highly anisotropic two-dimensional nanomaterial with attractive physical properties, good photothermal stability, and high photothermal conversion efficiency. , It is expected to be an ideal two-dimensional nanomaterial for photothermal detection.…”

Lateral Flow Strip Biosensors for Foodborne Pathogenic Bacteria via Direct and Indirect Sensing Strategies: A Review

“…POCT refers to a rapid analysis method at the patient’s bedside or outside the clinical laboratory, including dry chemical technology, immunochromatography, and emerging microfluidic biochip . The lateral flow strip biosensor (LFSB), combining dry chemistry and immunochromatography and originally proposed in the 1960s for the detection of serum proteins and human chorionic gonadotropin (hCG), , meets the POCT requirements and is now widely used in clinical diagnosis, food safety, and environmental monitoring. − …”