Sensitive determination of ethosuximide in human fluids by electromembrane extraction coupled with high performance liquid chromatography ultraviolet spectroscopy
Abstract:Ethosuximide (ETX) is a common antiepileptic drug in the first line of absence epilepsy. In this study, for the first time, an economical and efficient electro‐membrane (EME) method for determination of ETX in a complex biological matrix using HPLC‐UV has been developed. Factors affecting conventional EME were evaluated. 1‐Octanol was immobilized in a polypropylene membrane and a voltage of 35 V was applied between two platinum electrodes for 15 min. The pH of acceptor and donor phases for ionization of ETX wa… Show more
“…Table 1 lists the classification and characteristics of pharmaceutical pollutants. 22–45 Antiviral medications are used to treat viral infections such as influenza, hepatitis, polio, measles, and small pox by inhibiting the pathogen growth. Antiviral medicines are more active in nature during viral propagation.…”
Pharmaceutical pollutants, stemming from waste disposal, animal discharge, and drug manufacturing, pose health risks to humans and animals through their biological activity.
“…Table 1 lists the classification and characteristics of pharmaceutical pollutants. 22–45 Antiviral medications are used to treat viral infections such as influenza, hepatitis, polio, measles, and small pox by inhibiting the pathogen growth. Antiviral medicines are more active in nature during viral propagation.…”
Pharmaceutical pollutants, stemming from waste disposal, animal discharge, and drug manufacturing, pose health risks to humans and animals through their biological activity.
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