Sensitive determination of anticancer drug imatinib in spiked human urine samples by differential pulse voltammetry on anodically pretreated boron-doped diamond electrode

Brycht, Mariola; Kaczmarska, Kinga; Uslu, Bengi; Özkan, Síbel A.; Skrzypek, Sławomira

doi:10.1016/j.diamond.2016.05.007

Cited by 73 publications

(26 citation statements)

References 52 publications

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“…A cyclic voltammogram without linezolid was also showed in the graphs for comparison. The absence of any peak in the cathodic direction indicates that the oxidation process on the PG and CP electrodes of the linezolid molecule is not a reversible reaction . When the voltammograms of solutions containing 30 μg mL −1 linezolid were compared, it was observed that linezolid yielded an anodic oxidation peak (Ia) of 8.977 μA at +0.912 V at pH 4.0 and 3.799 μA at +0.865 V at pH 7.0 for PG and CP electrodes, respectively (Figure a‐b).…”

Section: Resultsmentioning

confidence: 99%

Analytical Determination of the Oxazolidinone Antibiotic Linezolid at a Pencil Graphite and Carbon Paste Electrodes

2019

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Electrochemical properties of linezolid, an antibiotic drug, using unmodified renewable pencil graphite and carbon paste electrodes, were investigated from pH 2 to 10 in Britton-Robinson buffer solution. Experimental studies were examined by square-wave (SW) and cyclic voltammetry (CV). Firstly, parameters affecting the performance of both electrode, such as electrode activation, support electrolyte selection, pH effect, interval of potentials, scan rates and voltammetric method parameters were investigated in detail by using square wave voltammetry. Linezolid was not reversibly oxidized in supporting electrolytes solutions, yielding well-defined peaks in the oxidation potential interval. Using the pencil graphite electrode (PGE), a linearity range between peak current and concentration was obtained between 0.01 and 0.2 μg mL À 1 (2.96 × 10 À 8 -5.93 × 10 À 7 M), other one, at carbon paste electrode (CPE), a linearity range between 0.1 and 7.5 μg mL À 1 (2.96 × 10 À 7 -2.22 × 10 À 5 M) was obtained by SWV. The selectivity, sensitivity, precision, and other validation parameters of the developed voltammetric method was evaluated. Lastly, the concentration of linezolid was examined in pharmaceutical and biological samples with standard addition technique.

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Section: Resultsmentioning

confidence: 99%

Analytical Determination of the Oxazolidinone Antibiotic Linezolid at a Pencil Graphite and Carbon Paste Electrodes

2019

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“…One appealing property of BDDEs is their resistance to fouling, as called to attention in the introduction of section 3. In this regard, Brycht et al [110] reported that an APT-BDDE had a higher resistance to surface fouling than a CPT-BDDE when used in the determination of the anticancer drug imatinib. As a consequence, better repeatability of the voltammetric measurements was attained using the APT-BDDE.…”

Section: Discussionmentioning

confidence: 99%

Analytical Applications of Electrochemically Pretreated Boron‐Doped Diamond Electrodes

et al. 2020

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The several outstanding properties of boron‐doped diamond electrodes (BDDEs) have allowed their application for various purposes, among them electrochemical sensing. However, the electrochemical response of many redox species on BDDEs can be strongly dependent on whether their surfaces are predominantly hydrogen‐ (HT) or oxygen‐terminated (OT). Fortuitously, electrochemical pretreatments themselves can be used to enrich in situ the BDEE surface in one or the other type of termination. The surface of a cathodically pretreated BBDE (CPT‐BDDE) becomes enriched in HTs, whereas that of an anodically pretreated BDDE (APT‐BDEE) becomes enriched in OTs. Thus, when suitable, the electrochemical activity of a BDDE for a given analyte may be tuned by electrochemical pretreatments, yielding enhanced sensing properties. The main purpose of this review is the compilation and discussion of papers published after 2009 reporting on electroanalytical applications based on a CPT‐BDDE or an APT‐BDDE. Procedures to perform proper electrochemical pretreatments are also discussed.

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“…Imatinib (IMA), a new generation of anticancer drug, was quantified by Brycht and coauthors using DPV . The authors used BR buffer pH 2.0 on BDD electrodes (doping level of 1000 ppm).…”

Section: Electroanalysis Of Pharmaceuticalsmentioning

confidence: 99%

Electroanalysis of Pharmaceuticals on Boron‐Doped Diamond Electrodes: A Review

et al. 2019

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diamond (BDD) electrodes possess outstanding physical, chemical, and electronic properties and have been successfully, yet in a limited way, explored in the electroanalysis of substances with therapeutic action (analgesics, antipyretics, antibiotics, anti-inflammatories, antihypertensives, antidepressants, vitamins, and others) in diverse milieus (pharmaceutical formulations, urine, serum, whole blood, surface waters, seawaters, groundwater, wastewaters, etc.). Therefore, in this Review, a broad overview of the available scientific information on recent progress and achievements of the application of bare or modified BDD electrodes to the bioanalytical and environmental detection of pharmaceutical compounds is presented. The main parameters, for example boron concentration, applied operational conditions during pretreatment, chemical and physical structure, and other influential factors on the electroanalytical BDD electrodes performance, are discussed.[a] Dr.

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Sensitive determination of anticancer drug imatinib in spiked human urine samples by differential pulse voltammetry on anodically pretreated boron-doped diamond electrode

Cited by 73 publications

References 52 publications

Analytical Determination of the Oxazolidinone Antibiotic Linezolid at a Pencil Graphite and Carbon Paste Electrodes

Analytical Determination of the Oxazolidinone Antibiotic Linezolid at a Pencil Graphite and Carbon Paste Electrodes

Analytical Applications of Electrochemically Pretreated Boron‐Doped Diamond Electrodes

Electroanalysis of Pharmaceuticals on Boron‐Doped Diamond Electrodes: A Review

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