Sensitive and rapid detection of Cr3+ in live cells by a red turn-on fluorescent probe

Jiang, Tiantian; Bian, Weiwei; Kan, Jianfei; Sun, Yanyan; Ding, Ning; Li, Wenjing; Zhou, Jin

doi:10.1016/j.saa.2020.118903

Cited by 29 publications

(7 citation statements)

References 39 publications

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“…In the human body, for a balanced diet, an adequate intake of Cr 3+ is 25–200 μg/day. Overload or deficiency of Cr 3+ may cause adverse health effects such as cardiovascular diseases, diabetes, and neurological disorders . This section discusses the Cr 3+ chemosensor.…”

Section: Cation Chemosensorsmentioning

confidence: 99%

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Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

et al. 2022

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Due to ever-increasing insights into their fundamental properties and photochromic behaviors, spiropyran derivatives are still a target of interest for researchers. The interswitching ability of this photochrome between the spiropyran (SP) and merocyanine (MC) isoforms under external stimuli (light, cations, anions, pH etc.) with different spectral properties as well as the protonation–deprotonation of its MC form allows researchers to use it suitably in sensing purposes by developing different colorimetric and fluorometric probes. Selective and sensitive recognition can be achieved by little modification of its SP moiety and functional groups. In this review, we emphasize the recent advancements (from 2019 to 2022) of spiropyran–merocyanine based fluorogenic and chromogenic probes for selective detection of various metal ions, anions, neutral analytes, and pH. We precisely explain their design strategies, sensing mechanisms, and biological and environmental applications. This review may accelerate the improvements in designing more advanced probes with innovative applications in the near future.

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Section: Cation Chemosensorsmentioning

confidence: 99%

“…Overload or deficiency of Cr 3+ may cause adverse health effects such as cardiovascular diseases, diabetes, and neurological disorders. 49 This section discusses the Cr 3+ chemosensor.…”

Section: Cation Chemosensorsmentioning

confidence: 99%

Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

et al. 2022

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“…Rhodamine and rhodamine derivatives have been applied widely as fluorescent probes owing to their remarkable optical characteristics including a high fluorescence quantum yield (Φ), a large molar extinction coefficient (ε), and longer excitation and emission wavelengths. 31 So far, many fluorescent probes utilizing rhodamine derivatives had been utilized to sense different cations including Cu 2+ , 32 Pb 2+ , 33 Cr 3+ , 34 Fe 3+ , 35 Al 3+ , 36 Zn 2+ , 37 and so forth. The sensing mechanism of these probes for cations is based on the transformation from a spirocyclic form into an open cyclic structure.…”

Section: Introductionmentioning

confidence: 99%

Rhodamine-Based Fluorescent Probe for Highly Selective Determination of Hg²⁺

Zhu

et al. 2022

ACS Omega

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The determination of mercuric ions (Hg 2+ ) in environmental and biological samples has attracted the attention of researchers lately. In the present work, a novel turn-on Hg 2+ fluorescent probe utilizing a rhodamine derivative had been constructed and prepared. The probe could highly sensitively and selectively sense Hg 2+ . In the presence of excessive Hg 2+ , the probe displayed about 52-fold fluorescence enhancement in 50% H 2 O/CH 3 CH 2 OH (pH, 7.24). In the meantime, the colorless solution of the probe turned pink upon adding Hg 2+ . Upon adding mercuric ions, the probe interacted with Hg 2+ and formed a 1:1 coordination complex, which had been the basis for recognizing Hg 2+ . The probe displayed reversible dual colorimetric and fluorescence sensing of Hg 2+ because rhodamine’s spirolactam ring opened upon adding Hg 2+ . The analytical performances of the probe for sensing Hg 2+ were also studied. When the Hg 2+ concentration was altered in the range of 8.0 × 10 –8 to 1.0 × 10 –5 mol L –1 , the fluorescence intensity showed an excellent linear correlation with Hg 2+ concentration. A detection limit of 3.0 × 10 –8 mol L –1 had been achieved. Moreover, Hg 2+ in the water environment and A549 cells could be successfully sensed by the proposed probe.

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“…Though fluorescence detection is quite convenient, probes that can detect target ions just by naked eyes have more widely application in critical situation or remote regions. Up to now, many splendid chemosensors have been developed for Cu 2 + detection, [6][7][8][9][10][11] whereas few probes for Cr 3 + detection are reported, [12][13][14][15] colorimetric sensors are even more scarce. Further, specific response to Cu 2 + and Cr 3 + ions by only one probe are full of challenge in very dilute solution because of either poor sensitivity or less resistance to interference during detection.…”

Section: Introductionmentioning

confidence: 99%

A New Spiropyran Hydrazone as an Unusual Colorimetric Sensor for Detection of Cu²⁺ and Cr³⁺ Based on Aggregation‐Induced Enhancement Effects in Aqueous Solvent Mixtures

Xiong

Liang

et al. 2022

ChemistrySelect

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Though many improvements have been made on fluorescence probes for respective detection of Cu 2 + and Cr 3 + , multiply detect of the ions by a simple colorimetric way in high water content solution sensors remains scarce. In this work, a novel spiropyran hydrazone,which shows aggregation-induced enhancement effects (AIEE) phenomena in EtOH (ethanol)/H 2 O and THF (tetrahydrofuran)/H 2 O media, has been developed. It can detect Cu 2 + colorimetrically having a sensitivity of 105 nM in EtOH/ H 2 O (40/60, v/v) with an unusual specific tandem-response toCr 3 + at a detection limit of 151 nM in addition with a wide pH range of 4-10. Mechanism investigations by HRMS, 1 H NMR and UV-Vis spectroscopy have verified that the response to Cr 3 + is based on the cooperative effect between NA-SP and Cu 2 + , instead of the replacement of Cu 2 + by Cr 3 + . Moreover, NA-SP shows a robust AIEE-caused recognition for Cu 2 + in THF/H 2 O (20/80, v/v) with a detection limit of 16.5 nM. Real water tests indicate that the probe has potential detection application for Cu 2 + in environmental situations. This contribution presents a new spiropyran sensor for the detection of Cu 2 + and Cr 3 + in aqueous solutions through an uncommonly colorimetric way.

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Sensitive and rapid detection of Cr3+ in live cells by a red turn-on fluorescent probe

Cited by 29 publications

References 39 publications

Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

Rhodamine-Based Fluorescent Probe for Highly Selective Determination of Hg²⁺

A New Spiropyran Hydrazone as an Unusual Colorimetric Sensor for Detection of Cu²⁺ and Cr³⁺ Based on Aggregation‐Induced Enhancement Effects in Aqueous Solvent Mixtures

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Sensitive and rapid detection of Cr3+ in live cells by a red turn-on fluorescent probe

Cited by 29 publications

References 39 publications

Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

Spiropyran–Merocyanine Based Photochromic Fluorescent Probes: Design, Synthesis, and Applications

Rhodamine-Based Fluorescent Probe for Highly Selective Determination of Hg2+

A New Spiropyran Hydrazone as an Unusual Colorimetric Sensor for Detection of Cu2+ and Cr3+ Based on Aggregation‐Induced Enhancement Effects in Aqueous Solvent Mixtures

Contact Info

Product

Resources

About

Rhodamine-Based Fluorescent Probe for Highly Selective Determination of Hg²⁺

A New Spiropyran Hydrazone as an Unusual Colorimetric Sensor for Detection of Cu²⁺ and Cr³⁺ Based on Aggregation‐Induced Enhancement Effects in Aqueous Solvent Mixtures