Sensitive and highly selective determination of vitamin B1 in the presence of other vitamin B complexes using functionalized gold nanoparticles as fluorophore

Shankar, Sekar; John, S. Abraham

doi:10.1039/c5ra09165a

Cited by 19 publications

(9 citation statements)

References 42 publications

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“…A limit of detection of 54 n m was reported with an assay range from 0.15 to 3.5 μ m . Other researchers have attributed the aggregation of negatively charged AuNPs in the presence of thiamine to a neutralization of the NP surface charge . In a fluorescence‐based approach, captopril‐modified yttrium:europium NPs (Y 2 O 3 :Eu NPs) were found to exhibit an increase in fluorescence in the presence of increasing concentrations of thiamine .…”

Section: Analytical Methods Based On Chemical Propertiesmentioning

confidence: 99%

Thiamine Assays—Advances, Challenges, and Caveats

et al. 2017

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Thiamine (vitamin B1) is essential to the health of all living organisms and deficiency has long been associated with diseases in animals such as fish, birds, alligators, and domesticated ruminant mammals. Thiamine is also implicated in several human diseases including Alzheimer's, diabetes, dementia, depression and, most notably, Wernicke–Korsakoff syndrome and Beriberi disease. Yet, highly sensitive and specific detection of thiamine remains an analytical challenge, as pM to nm levels of thiamine need to be detected in environmental and human samples, respectively, various phosphorylated variants need to be discriminated, and rapid on‐site detection would be highly desirable. Furthermore, appropriate sample preparation is mandatory, owing to the complexity of the relevant sample matrices including fish tissues, ocean water, and body fluids. This Review has two objectives. First, it provides a thorough overview of analytical techniques published for thiamine detection over the last 15 years. Second, it describes the principles of analytical approaches that are based on biorecognition and may open up new avenues for rapid and high‐throughput thiamine analysis. Most notably, periplasmic binding proteins, ribozymes, and aptamers are of particular interest, as they function as bioaffinity recognition elements that can fill an important assay technology gap, owing to the unavailability of thiamine‐specific commercial antibodies. Finally, the authors provide brief evaluations of key outcomes of the major assay concepts and suggest how innovative techniques could help develop sensitive and specific thiamine analytical test systems.

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Section: Analytical Methods Based On Chemical Propertiesmentioning

confidence: 99%

Thiamine Assays—Advances, Challenges, and Caveats

et al. 2017

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“…Experimental Judd-Ofelt intensity parameters (Ω 2 , Ω 4 ), lifetime (τ) values obtained from a monoexponential fitting in the decay curves shown in Figure S5, radiative (A rad ) e nonradiative (A nrad ) rates obtained from the emission spectra and equations (3), (4) and (6), Eu 3+ 5 D 0 level quantum efficiency (η) obtained from equations (5)- (7), and emission quantum yield (QY) at 270 nm excitation for the Eu 3+ -doped molybdates.…”

Section: Tablementioning

confidence: 99%

“…[1][2][3][4][5] This wide field of applications comes from the synergism between the phosphor luminescence and the AuNPs properties, such as good conductivity and favorable biocompatibility [6]. Therefore, in the present study, the Y 2 (MoO 4 ) 3 :Eu 3+ /Au composite is introduced aiming to combine both phosphor's and Au NPs properties which can provide bifunctionalities for high sensitivity/resolution fluorescence imaging and high quality in the detection of different molecules [7].…”

Section: Introductionmentioning

confidence: 99%

Red phosphor based on Eu3+-doped Y2(MoO4)3 incorporated with Au NPs synthesized via Pechini's method

et al. 2018

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Structural, morphological and spectroscopic characterization of the Eu 3+-doped Y 2 (MoO 4) 3 red phosphor incorporated with Au nanoparticles (Au NPs) synthesized via Pechini's method is reported in the present study. In order to evaluate the Au NPs and Eu 3+ ions influence on the molybdate structure, the Y 2 (MoO 4) 3 , Y 2 (MoO 4) 3 :Eu 3+ , Y 2 (MoO 4) 3 /Au and Y 2 (MoO 4) 3 :Eu 3+ /Au samples were produced and fully investigated. All samples obtained at relatively low temperature, i.e., 650°C, show molybdate as the unique phase with high crystallinity assisted by both Eu 3+ ions and Au NPs. Water molecules detected in the molybdate structure probably are distorting MoO 4 , YO 6 and EuO 6 polyhedra similarly to the Au NPs incorporated in the same lattice. These Au NPs are spherical-shaped with a diameter near to 46 nm and they are located on the molybdate particle surface. The Eu 3+-doped phosphors, with or without the presence of Au NPs, exhibit intense red luminescence characteristic of the Eu 3+ ion inserted in low-symmetry sites. However, the Au NPs increase the radiative emission rate and absolute quantum yield of the Eu 3+ 5 D 0 emitter state due to the excitation field enhancement caused by the local surface plasmon resonance absorption effect of gold nanoparticles, which was confirmed by diffuse reflectance measurements. Finally, the Eu 3+ quantum efficiency enhancement to 92% played by the gold nanoparticles and the high red color purity qualify the obtained phosphor for photonic applications.

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“…4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate (AHMP) is an interesting ligand. It contains a thiol group which can self-assemble on the AuNP surface [29,30]. Additionally, the amine and hydroxyl groups available in AHMP are free from binding.…”

Section: Introductionmentioning

confidence: 99%

A Transparency Sheet-Based Colorimetric Device for Simple Determination of Calcium Ions Using Induced Aggregation of Modified Gold Nanoparticles

Duenchay

Chailapakul

Siangproh

2019

IJMS

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A simple and novel transparency sheet-based colorimetric detection device using gold nanoparticles (AuNPs) modified by 4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate (AHMP) was fabricated and developed for the determination of calcium ions (Ca2+). The detection was based on a colorimetric reaction as a result of the aggregation of modified AuNPs induced by Ca2+ due to the ability to form strong electrostatic interactions between positively charged Ca2+ and negatively charged modified AuNPs. Probe solution changes color from red to blue in the presence of Ca2+ and can be observed by the naked eyes. To verify the complete self-assembly of the AHMP onto the AuNP surface, the modified AuNPs were characterized using ultraviolet–visible spectroscopy and zeta potential measurements. Under optimal conditions, a quantitative linearity was 10 to 100 ppm (R2 = 0.9877) with a detection limit of 3.05 ppm. The results obtained by the developed method were in good agreement with standard atomic absorption spectrometry (AAS) results and demonstrated that this method could reliably measure Ca2+. Overall, this novel alternative approach presents a low-cost, simple, sensitive, rapid, and promising device for the detection of Ca2+.

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Sensitive and highly selective determination of vitamin B1 in the presence of other vitamin B complexes using functionalized gold nanoparticles as fluorophore

Cited by 19 publications

References 42 publications

Thiamine Assays—Advances, Challenges, and Caveats

Thiamine Assays—Advances, Challenges, and Caveats

Red phosphor based on Eu3+-doped Y2(MoO4)3 incorporated with Au NPs synthesized via Pechini's method

A Transparency Sheet-Based Colorimetric Device for Simple Determination of Calcium Ions Using Induced Aggregation of Modified Gold Nanoparticles

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