Sensitisation to aeroallergens in relation to asthma and other allergic diseases in Angolan children: a cross-sectional study

Arrais, Margarete; Lulua, Ofélia; Quifica, Francisca; Rosado‐Pinto, J.; Gama, Jorge; Brito, Miguel; Taborda-Barata, Luís

doi:10.1016/j.aller.2019.10.005

Cited by 4 publications

(4 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The author showed that among 100 children aged 5-14 and suffering from asthma that participated in the study, 54 manifested the symptoms of the allergy to house dust mites [25,26]. Moreover, another study conducted in Bengo Province in Angola, wherein children aged 5-14 were subjected to cross-sectional observations from September to November, 82 out of 1023 children had a positive SPT (skin prick test) result for aeroallergens, while 70.2% of 92 positive SPT were positive for house dust mites [27]. Inhaled polyallergy is also quite common in the paediatric population, mainly in older children.…”

Section: Discussionmentioning

confidence: 99%

Allergic and non-allergic asthma in children hospitalized in the University Children’s Hospital in Lublin in 2016-2020

Szuba

Wawryk‐Gawda

Brzuszkiewicz

et al. 2022

Current Issues in Pharmacy and Medical Sciences

View full text Add to dashboard Cite

Introduction. Bronchial asthma is a common disease characterized by chronic inflammation of the airways. Paediatric asthma is still a current problem and children with exacerbation frequently are hospitalized. The aim of the study was to determine the prevalence of allergic and non-allergic asthma in children hospitalized at the Department of Paediatric Pulmonology and Rheumatology of the University Children’s Hospital in Lublin in 2016-2020, and to analyze the most common allergens associated with allergic asthma. Materials and methods. The study group consisted of 667 patients, aged 6 to 215 months (average 64 months). The data collected for this retrospective study includes: gender, age, month, quarter of year, and year of hospitalization, type of asthma and type of allergens. Results. We observed a decrease of hospitalization in the analyzed years: in 2016 – 160 children, and in 2020 – 74. Children with allergic asthma (375 children) were more frequently hospitalized than patients with non-allergic asthma, and we found correlations between age and type of asthma and between age and type of allergy. Non-allergic asthma was observed in the youngest children, while in older children, allergic-asthma dominated. We also observed significant differences in children’s hospitalization depending on the season of the year. The most frequent allergen causing asthma was house dust mites. Conclusions. The incidence of hospitalizations caused by asthma exacerbation is declining. Among the youngest population, exacerbations of asthma related to respiratory tract infection predominate, while in the older, allergy to inhalation allergens is the main cause.

show abstract

Section: Discussionmentioning

confidence: 99%

Allergic and non-allergic asthma in children hospitalized in the University Children’s Hospital in Lublin in 2016-2020

Szuba

Wawryk‐Gawda

Brzuszkiewicz

et al. 2022

Current Issues in Pharmacy and Medical Sciences

View full text Add to dashboard Cite

show abstract

“…Around the world, reports of allergy disorders as allergic rhinitis, asthma, and atopic dermatitis have increased and are highly prevalent [1][2][3][4]. There are 10 to 30% of adults and up to 40% of children impacted, according to epidemiologic research [3].…”

Section: Introductionmentioning

confidence: 99%

Recent Updates of Immunotherapy for Allergic Rhinitis in Children

Lin

Liao

et al. 2023

Curr Otorhinolaryngol Rep

View full text Add to dashboard Cite

Purpose of Review Allergen immunotherapy (AIT) is a novel treatment approach with disease-modifying and preventative benefits that are not shared with other strategies for treating allergic illnesses. It has been demonstrated to be safe and effective in children. This review provides the most recent information on AIT in children as well as any pertinent updates. Recent Findings Although there is not a standard way to begin AIT, there are clear indications for AIT. Each case needs to be evaluated on its own by weighing the pros and downsides. AIT has been proven to significantly improve symptoms and quality of life in children with allergic illness, reduce medication use, stop the development of new allergen sensitizations, and stop the progression of allergic rhinitis to asthma. Novel approaches are under investigation to overcome some known AIT disadvantages. Summary This review provides a thorough summary of the most recent research and updates on AIT in children.

show abstract

“…Although there are reports indicating an increasing prevalence of allergy in Zimbabwe [ 9 – 11 ], these studies suffer from a pro-urban and potentially an economic bias being derived from patients who visited hospitals or private clinics with suspected allergic symptoms. In Africa, very few studies have been done in rural areas [ 12 , 13 ]. While it is believed that allergy prevalence is lower in rural areas due to lifestyle and environment factors in low and high income countries, the situation could be changing [ 3 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Sensitisation to Imbrasia belina (mopane worm) and other local allergens in rural Gwanda district of Zimbabwe

Ndlovu

Chimbari

Ndarukwa

et al. 2022

Allergy Asthma Clin Immunol

View full text Add to dashboard Cite

Background The prevalence of allergic diseases is increasing in Zimbabwe and the data relate to local as well as exotic allergen sources. As entomophagy, the practice of eating insects, is a recognised source of local allergens, we sought to measure the prevalence of and risk factors for sensitisation to Imbrasia belina (mopane worm), a popular edible insect. This was investigated alongside other locally relevant allergens in a rural community in Gwanda district, south of Zimbabwe. Methods A cross sectional study was conducted among 496 adults and children aged 10 years and above in Gwanda district, a mopane worm harvesting area in Zimbabwe. Data on individual characteristics and mopane worm exposure factors were collected using questionnaires. Sensitivity to allergens was assessed by performing skin prick tests at a local clinic using 10 different commercial allergen extracts (Stallergenes, France) and in-house extracts of mopane worm (Imbrasia belina) and mopane leaves (Colophospermum mopane). Data were analysed using Stata version 13 software. Results The prevalence of sensitisation to at least one allergen was 31.17% (n = 144). The prevalence of atopy was higher in adults (33.33%) than in children (23.53%) (p = 0.059). The commonest inhalant allergen sources were mopane worm (14.29%), Tyrophagus putrescentiae (14.29%), mopane leaves (13.42%), Alternaria alternata (6.49%) and Dermatophagoides pteronyssinus (6.49%). Polysensitisation was demonstrated in the study population and of the 108 participants (75%) who were sensitised to two or more allergens, 66 (61%) were women. Sensitisation to mopane worm and mopane leaves often clustered with Tyrophagus putrescentiae amongst adults. Adjusted logistic regression analyses between mopane worm sensitisation and self-reported exposure variables showed that sensitisation was more likely amongst mopane worm harvesters (OR = 1.92, 95%CI = 0.77–4.79), those who cooked or roasted mopane worms during harvesting (OR = 2.69, 95%CI = 0.78–9.31) and harvesting without personal protective equipment (PPE) (OR = 2.12, 95%CI = 0.83–5.44) compared to non-harvesters. Conclusion Atopic sensitization was common in this mopane worm harvesting community in Gwanda district of Zimbabwe. There was frequent co-sensitisation of mopane worm and mopane leaves with Tyrophagus putrescentiae in children and adults. It is important to determine the clinical relevance of our findings, particularly relating to mopane worm sensitisation.

show abstract

Sensitisation to aeroallergens in relation to asthma and other allergic diseases in Angolan children: a cross-sectional study

Cited by 4 publications

References 34 publications

Allergic and non-allergic asthma in children hospitalized in the University Children’s Hospital in Lublin in 2016-2020

Allergic and non-allergic asthma in children hospitalized in the University Children’s Hospital in Lublin in 2016-2020

Recent Updates of Immunotherapy for Allergic Rhinitis in Children

Sensitisation to Imbrasia belina (mopane worm) and other local allergens in rural Gwanda district of Zimbabwe

Contact Info

Product

Resources

About