Sensing system for mimicking cancer cell–drug interaction

Artificial antibody created by conformational reconstruction of the complementary-determining region on gold nanoparticles

“…Nanotechnology is one of the most active fields, with great expectations such as revolutionizing cancer diagnosis and therapy ( 1 , 2 ). After decades of extensive studies, nowadays scientists can easily control the size and shape of many nanoparticles (NPs), yet there seems still a long way to go to fulfill their expectations ( 3 ).…”

Smartphones for sensing

“…It is well known that material plays an important role in chemical sensing [6][7][8][9][10]. Here, we focus on the study of instruments, especially mobile phone devices.…”

An insight into the cells’ glycans and lectin-glycosensing sites

“…However, the weak binding affinity and non-covalent characteristics of the lectin glyco-interactive sites can be enhanced dramatically by multivalent binding approaches [5]. Among these, the most powerful one is sensing the structural motifs and intensity of the accessible cell surface sialylation constellations [6,7]. Djansugurova group from Kazakh Institute of General Genetics and Cytology, in collaboration with Ahmed group in the University of Maryland, reported in a preliminary communication the restoration of surface sialylation sites in a T47D breast cancer line compared to HB4A normal cells after sialic acid supplementation under conditions of nutrient deprivation [8].…”