Sensing Proteins With Adaptive Metal Nanostructures

Hollow metal island films as plasmonic sensors produced by galvanic replacement

“…In a similar fashion, restructuring of metal island films as a result of their interaction with proteins has been previously observed. This adaptability phenomenon was exploited to increase the island films sensitivity to the Raman signal of these proteins caused by the increase of hot spots sites [44,27].…”

“…Metal islands films are appealing building blocks for cost-efficient and large-area production of plasmonic devices since they can be obtained by well-established thin film techniques and their optical properties can be broadly tuned by adjusting the fabrication conditions [24,25]. The characteristic large nanoparticle density and small interparticle distance makes these films efficient plasmonic sensors [26,27]. Among noble metals, Ag shows the most prominent island growth in standard evaporation process.…”

Cylindrical posts of Ag/SiO2/Au multi-segment layer patterns for highly efficient surface enhanced Raman scattering

“…This is attributed to the fact that the refractive index of the Ag/Au hybrid system is considerably altered by introducing a dielectric layer, resulting in optimized SPR interaction in the bimetallic system. Various dielectric layers such as SiO 2 [26][27][28][29] and 11-amino-1-undecanethiol (AUT) [30] have been used as interlayer materials. Thus, it is expected that the patterned multi-segment containing Ag/dielectric/Au layer can provide a high performance of SERS with high sensitivity, reproducibility and long-term stability, because the periodic bimetallic structure allows reproducibility and long-term stability while the interlayer can enhance the sensitivity.…”