Sense of smell disorder and health-related quality of life.

Smeets, Monique A. M.; Veldhuizen, Maria G.; Galle, Sara A; Gouweloos, Juul; Haan, Anne-Marie J. A. de; Vernooij, J C M; Visscher, Floris; Kroeze, Jan H.A.

doi:10.1037/a0017502

Cited by 119 publications

(106 citation statements)

References 36 publications

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“…We previously showed that among older adults aged 60 and over, 27.0 % had olfactory impairment [3]. While the prevalence of impaired olfaction in the 'healthy' aging population could be greater than previously thought [3], many older people may not raise the issue of their loss of the sense of smell because they are not always aware of it [4,5]. Moreover, the potential importance of olfaction is not well documented, compared with that of other senses such as vision and hearing.…”

Section: Introductionmentioning

confidence: 94%

Olfactory impairment in older adults is associated with poorer diet quality over 5 years

et al. 2015

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Section: Introductionmentioning

confidence: 94%

Olfactory impairment in older adults is associated with poorer diet quality over 5 years

et al. 2015

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“…Smell and taste are, to some extent, intrinsic objective properties but also subjective qualities that vary from person to person and are shaped by experiences and physiological changes accumulated throughout life, commencing with the early uterine environment. The perception of smell and taste, in return, greatly influences emotions, psychological well-being, and physiological and metabolic processes, as well as interpersonal relationships and social associations [5,21,22,23,24]. …”

Section: Discussionmentioning

confidence: 99%

Smell and Taste to Improve Nutrition in Very Preterm Infants: A Randomized Controlled Pilot Trial

Beker

Opie²,

Noble³

et al. 2016

Neonatology

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Background: The perception of smell and taste, though present early in development, is not routinely considered in the care of preterm infants. Smell and taste are known to increase gut motility, insulin secretion, and the release of appetite, digestive and metabolic hormones. Objective: We aimed to investigate the effect of regular smell and taste on the time from birth to full enteral feeds, and the feasibility of the study protocol in very preterm infants. Methods: In a randomized controlled trial, infants <29 weeks' postmenstrual age (PA) were assigned to receive either the smell and taste of milk before each feed or to have no exposure to the smell and taste of milk (control). Results: Infants in the treatment group (n = 28) and control group (n = 23) were born at a mean (SD) PA of 26.7 (1.5) and 27.2 (1.4) weeks, respectively. They reached full enteral feeds at a median (IQR) of 13.5 (10.0-19.0) and 15.5 (11.0-22.0) days, respectively. Survival analysis showed an adjusted hazard ratio of 1.63 (95% confidence interval 0.91-2.91; p = 0.10) for the effect on the time to establish full enteral feeds. Repeated-measures analysis indicated significant group differences in weight z scores at 36 weeks' PA and at discharge in favor of the intervention (p < 0.05). Conclusion: These data indicate that the smell and taste of milk may improve milk tolerance and weight in preterm infants. The role of regular smell and taste in promoting enteral nutrition and growth in preterm infants merits a larger trial powered to detect important outcomes.

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“…It provides critical information about the environment and plays an important role in safety and survival, nutrition, social interactions, sexual function and maintenance of quality of life [6][7][8]. Loss of smell and taste sensations may result in depression [9].…”

Section: Introductionmentioning

confidence: 99%

Association between diabetes mellitus and olfactory dysfunction: current perspectives and future directions

et al. 2017

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The increasing global prevalence of diabetes mellitus presents a significant challenge to healthcare systems today. Although diabetic retinopathy, nephropathy and neuropathy are well-established complications of diabetes, there is a paucity of research examining the impact of dysglycaemia on the olfactory system. Olfaction is an important sense, playing a role in the safety, nutrition and quality of life of an individual, but its importance is often overlooked when compared with the other senses. As a result, olfactory dysfunction is often underdiagnosed. The present review article aims to present and discuss the available evidence on the relationship between diabetes and olfaction. It also explores the associations between olfactory dysfunction and diabetes complications that could explain the underlying pathogenesis. Finally, it summarizes the putative pathological mechanisms underlying olfactory dysfunction in diabetes that require further investigation.

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Sense of smell disorder and health-related quality of life.

Abstract: Once a smell dysfunction is recognized, interventions aiming at dealing with the loss of smell as a source of information and enjoyment, as well as at improvement of emotional wellbeing, social interaction, energy, and depression should be considered.

Cited by 119 publications

References 36 publications

Olfactory impairment in older adults is associated with poorer diet quality over 5 years

Olfactory impairment in older adults is associated with poorer diet quality over 5 years

Smell and Taste to Improve Nutrition in Very Preterm Infants: A Randomized Controlled Pilot Trial

Association between diabetes mellitus and olfactory dysfunction: current perspectives and future directions

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