1994
DOI: 10.1159/000106704
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Senile Dementia of Extreme Aging: A Common Disorder of Centenarians

Abstract: To study dementia in the extremely aged, I evaluated 40 centenarians with a mean age of 101.6 years (range: 100–107). The group completed 5.8 years of education, on average. Bradyphrenia and bradykinesia were common and most had impaired awareness and concern. The Folstein Mini-Mental State Exam and Washington University''s Clinical Dementia Rating Scale indicated moderately advanced dementia in more than half; 4 had a clinical pattern that suggested senile dementia of the Alzheimer''s type. A common pattern o… Show more

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Cited by 16 publications
(13 citation statements)
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“…One major consequence of an ongoing demographic aging is a substantial increase in the occurrence of dementia [13,32], in Germany as well as in other countries. Different studies conclude that senile dementia is strongly age-related [28,33,34], Depending on the specific instruments to diagnose dementia, the prevalence rates of dementia among the oldest old is esti mated to be between 16 and 43% in Germany [28], With respect to this observation the low frequency of dementia among elderly hospital patients is remarkable. The low prevalence rate of dementia in our sample may be seen as an indirect sign of a general underestimation of this diag nosis, which has already been described in the literature [10,11].…”
Section: Discussionmentioning
confidence: 99%
“…One major consequence of an ongoing demographic aging is a substantial increase in the occurrence of dementia [13,32], in Germany as well as in other countries. Different studies conclude that senile dementia is strongly age-related [28,33,34], Depending on the specific instruments to diagnose dementia, the prevalence rates of dementia among the oldest old is esti mated to be between 16 and 43% in Germany [28], With respect to this observation the low frequency of dementia among elderly hospital patients is remarkable. The low prevalence rate of dementia in our sample may be seen as an indirect sign of a general underestimation of this diag nosis, which has already been described in the literature [10,11].…”
Section: Discussionmentioning
confidence: 99%
“…SST has been widely accepted for the healthy elderly [19] and whether it applies to AD (which some researchers see as extreme aging, (e.g. [20]) is, I believe, worthwhile as we move towards more individual-based treatments.…”
Section: Methodsmentioning
confidence: 99%
“…Cognitive function and dementia have been examined in a number of centenarian studies (30,59,62,63,(108)(109)(110)(111)(112)(113)(114)(115). It can be very difficult to diagnose mild dementia in centenarians because of the frequent incidence of reduced vision and hearing.…”
Section: Do Healthy Centenarians Exist?mentioning
confidence: 99%