Senile Cataract in Patients with Diabetes with and Without Diabetic Retinopathy: A Community-Based Comparative Study

Alabdulwahhab, Khalid

doi:10.1007/s44197-021-00020-6

Cited by 12 publications

(8 citation statements)

References 35 publications

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“…Olafsdottir et al showed that the prevalences of significant cortical, posterior subcapsular, and nuclear cataracts were 65.5%, 42.5%, and 48.0%, respectively, in the type 2 diabetes population [ 5 ]. These results are consistent with most of the previous studies [ 6 , 7 , 8 , 9 , 10 ]. Two studies reported contrasting findings, that is, NS was identified as the predominant subtype [ 3 , 11 ].…”

Section: Introductionsupporting

confidence: 94%

Current Approach to the Pathogenesis of Diabetic Cataracts

Mrugacz

Pony-Uram

Bryl

et al. 2023

IJMS

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Cataracts remain the first or second leading cause of blindness in all world regions. In the diabetic population, cataracts not only have a 3–5 times higher incidence than in the healthy population but also affect people at a younger age. In patients with type 1 diabetes, cataracts occur on average 20 years earlier than in the non-diabetic population. In addition, the risk of developing cataracts increases with the duration of diabetes and poor metabolic control. A better understanding of the mechanisms leading to the formation of diabetic cataracts enables more effective treatment and a holistic approach to the patient.

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Section: Introductionsupporting

confidence: 94%

Current Approach to the Pathogenesis of Diabetic Cataracts

Mrugacz

Pony-Uram

Bryl

et al. 2023

IJMS

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“…Consistently, a community-based cross-sectional study done in Saudi Arabia showed that among 668 eyes from 334 patients with T2DM, 237 eyes (35.5%) had cataract (28). Similar to the findings of Becker et al, diabetic patients with cataract were associated with a longer duration of diabetes.…”

Section: Epidemiology Of Diabetic Macular Edemasupporting

confidence: 76%

Optimizing treatment for diabetic macular edema during cataract surgery

et al. 2023

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Diabetic macular edema (DME) causes visual impairment in diabetic retinopathy (DR). Diabetes mellitus is a global epidemic and diabetic individuals are at risk of developing DR. Approximately 1 in 10 diabetic patients suffers from DME, which is the commonest cause of vision-threatening DR at primary-care screening. Furthermore, diabetes predisposes to a higher frequency and a younger onset of cataract, which further threatens vision in DME patients. Although cataract extraction is an effective cure, vision may still deteriorate following cataract surgery due to DME progression or recurrence, of which the risks are significantly higher than for patients without concurrent or previous history of DME at the time of operation. The management of pre-existing DME with visually significant cataract is a clinical conundrum. Deferring cataract surgery until DME is adequately treated is not ideal because of prolonged visual impairment and maturation of cataract jeopardizing surgical safety and monitoring of DR. On the other hand, the progression or recurrence of DME following prompt cataract surgery is a profound disappointment for patients and ophthalmic surgeons who had high expectations for postoperative visual improvement. Prescription of perioperative anti-inflammatory eye drops is effective in lowering the risk of new-onset DME after cataract surgery. However, management of concurrent DME at the time of cataract surgery is much more challenging because DME is unlikely to resolve spontaneously even with the aid of anti-inflammatory non-steroidal or steroid eye drops. A number of clinical trials using intravitreal injection of corticosteroids and anti-vascular endothelial growth factor (anti-VEGF) as first-line therapy have demonstrated safety and efficacy to treat DME. These drugs have also been administered perioperatively for the prevention of DME worsening in patients undergoing cataract surgery. This article reviews the scientific evidence to guide ophthalmologists on the efficacy and safety of various therapies for managing patients with DME who are particularly vulnerable to cataract surgery-induced inflammation, which disintegrates the blood–retinal barrier and egression of fluid in macular edema.

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“…Other studies by Alabdul Wahhab KM et al and Wen L et al reported cataract prevalence rates of 35.5% and 36.4%, respectively, which are lower than the findings of this study. 4,5 The higher prevalence of cataract in this population highlights the need for specific awareness programs and interventions to reduce their occurrence. Although diabetes may not be the direct cause of cataract, it is known to be a contributing factor.…”

Section: Discussionmentioning

confidence: 99%

Investigating the influence of clinico-socio-demographic factors on ocular disorders in diabetes mellitus: A study from western Uttar Pradesh

Singh,

Sinha,

Chaturvedi

et al. 2024

IJCEO

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The study aims to investigate the correlation between clinico-socio-demographic factors and ocular diseases in diabetic patients and assess the knowledge of patients with diabetes mellitus regarding diabetes-related ocular diseases.This cross-sectional study examined 120 diabetic patients referred from the Diabetic clinic. Clinico-socio-demographic data was analysed to understand ocular disease correlations and guide interventions. Anthropometric and medical history data were gathered using a self-developed questionnaire. Biochemical parameters, fasting, postprandial glucose and HbA1c levels were measured. Assessment of Awareness and experiences of diabetic ocular disease with a scoring system was done. Ocular exams (slit lamp, intraocular pressure, and fundus checks) were conducted by an ophthalmologist in the Ophthalmology OPD. The study found that the most prevalent ocular disease in diabetic patients was cataract (52.5%), followed by diabetic retinopathy (13.33%). Demographic factors showed significant associations with ocular diseases (p < 0.05). The research identified a notable ocular disease prevalence among diabetes patients, with socioeconomic factors impacting treatment access and causing lasting eye damage. Awareness of diabetes and its complications was moderate, highlighting the need for enhanced education via diverse channels and healthcare facilities to enable early detection and improved outcomes.

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Senile Cataract in Patients with Diabetes with and Without Diabetic Retinopathy: A Community-Based Comparative Study

Cited by 12 publications

References 35 publications

Current Approach to the Pathogenesis of Diabetic Cataracts

Current Approach to the Pathogenesis of Diabetic Cataracts

Optimizing treatment for diabetic macular edema during cataract surgery

Investigating the influence of clinico-socio-demographic factors on ocular disorders in diabetes mellitus: A study from western Uttar Pradesh

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