Seneca and Nature

Rosenmeyer, Thomas G.

doi:10.1353/are.2000.0005

Cited by 6 publications

(4 citation statements)

References 20 publications

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“…The melting points of the products were determined on a XT-4 binocular microscope (Beijing Tech Instrument Co., China) and were not corrected. 1 H and 13 C NMR (solvent DMSO-d 6 ) spectra were recorded on a JEOL-ECX 500 NMR spectrometer at room temperature using TMS as an internal standard. Elemental analysis was performed on an Elementar Vario-III CHN analyzer.…”

Section: Discussionmentioning

confidence: 99%

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Synthesis and Antibacterial Activity of Novel Substituted Purine Derivatives

Gao

Hong

et al. 2015

Journal of Heterocyclic Chem

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A series of novel N‐substituted‐2‐(6‐morpholino‐9H‐purin‐9‐yl)acetamide and 4‐(9‐((5‐substituted‐1,3,4‐oxadiazole/thiadiazole‐2‐yl)methyl)‐9H‐purin‐6‐yl)‐morpholine derivatives were synthesized and evaluated their antibacterial activities against rice bacterial leaf blight and tobacco bacterial wilt caused by Xanthomonas oryzae pv. oryzae (Xoo) and Ralstonia solanacearum (R. solanacearum) via the turbidimeter test in vitro. Antibacterial bioassay indicated that most compounds demonstrated good inhibitory effect against Xoo and R. solanacearum. Especially, compound 6a demonstrated the best inhibitory effect against Xoo with half‐maximal effective concentration (EC50) value of 8.39 μg/mL, which was even better than those of commercial agents Bismerthiazol and Thiodiazole copper. The synthesized purine derivatives containing amide and 1,3,4‐oxadiazole/thiadiazole moieties exhibited excellent antibacterial activities against Xanthomonas oryzae pv. oryzae and R. solanacearum in vitro.

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Section: Discussionmentioning

confidence: 99%

“…Purines are the most ubiquitous components containing nitrogen heterocycle in nature [1]. They are constituted for DNA and RNA and consequently of fundamental importance in life processes [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Antibacterial Activity of Novel Substituted Purine Derivatives

Gao

Hong

et al. 2015

Journal of Heterocyclic Chem

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“…In addition, these compounds have been reported to show a broad spectrum of pharmaceutical and physiological activities [7][8][9][10][11]. Purines are constituents of DNA and RNA and consequently of fundamental importance in life processes [12,13]. They act as hormones and neurotransmitters and are present in some coenzymes [14].…”

Section: Introductionmentioning

confidence: 99%

“…They act as hormones and neurotransmitters and are present in some coenzymes [14]. Purine derivatives have been used as the intermediate structure for synthesis of some heterocyclic compounds with variety of pharmacological properties such as antirhinovirus [15], anti-HIV-1 [16], antimicrobial, antibacterial, antifungal [12,13], antiviral, and antitumor activity as kinase inhibitors [14,17,18]. Pteridines are also important heterocyclic compounds for many biological processes, such as amino acid metabolism, nucleic acid synthesis, cancer, and neurotransmitter and dihydrofolic acid synthesis in many microorganisms.…”

Section: Introductionmentioning

confidence: 99%

Solvent‐free Synthesis of 2,6‐Dihydroxy‐9H‐purin and Pteridine Derivatives

Nami

Tizkar

Zardost

2017

Journal of Heterocyclic Chem

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5,6‐Diaminopyrimidin‐2,4‐diol 1 was reacted with 1,4‐d‐gluconolactone 2, 6‐chloro‐4‐cyclopropyl‐7‐floro‐1,4‐dihydro‐1‐oxonaphthalen‐2‐carboxilic acid 4, (3S)‐9,10‐difloro‐3,7‐dihydro‐3‐methyl‐7‐oxo‐2H‐[1,4]oxazino[2,3,4‐ij]quinolin‐6‐carboxylic acid 6, and dimethylacetylendicarboxylate to afford 1‐(2,6‐dihydroxy‐9H‐purin‐8‐yl)‐sorbitol 3, 7‐chloro‐1‐cyclopropyl‐6‐flouro‐3‐(2,6‐dihydroxy‐9H‐purin‐8‐yl)quinoline‐4(1H)‐one 5, 9,10‐difluoro‐2,3‐dihydro‐6‐(2,6‐dihydroxy‐9H‐purin‐8‐yl)‐3‐methyl‐[1,4]oxazine[2,3,4‐ij]quinoline‐7‐one 7, and (2,4‐dihydroxy‐6‐oxo‐5,8‐dihydro‐6H‐pteridine‐7‐yiliden)‐acetic acid methyl ester 9, respectively. The synthesized compounds characterized by IR, 1H‐NMR, 13C‐NMR, GC‐mass, and elemental analysis.

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The Ethics of the Family in Seneca

Gloyn

2017

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This book is the first extensive study of the role of the family in the work of Seneca. It offers a new way of reading philosophy that combines philosophical analysis with social, cultural and historical factors to bring out the ways in which Stoicism presents itself as in tune with the universe. The family serves a central role in an individual's moral development - both the family as conventionally understood, and the wider conceptual family which Stoicism constructs. Innovative readings of Seneca's work bring out the importance of the family to his thought and how it interacts with other Stoic doctrines. We learn how to be virtuous from observing and imitating our family, who can be biological relatives or people we choose as our intellectual ancestors. The Ethics of the Family in Seneca will be of particular interest to researchers in Roman Stoicism, imperial culture and the history of the family.

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Seneca and Nature

Cited by 6 publications

References 20 publications

Synthesis and Antibacterial Activity of Novel Substituted Purine Derivatives

Synthesis and Antibacterial Activity of Novel Substituted Purine Derivatives

Solvent‐free Synthesis of 2,6‐Dihydroxy‐9H‐purin and Pteridine Derivatives

The Ethics of the Family in Seneca

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