2023
DOI: 10.1007/s00247-023-05794-4
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Semiquantitative analysis of cerebral [18F]FDG-PET uptake in pediatric patients

Álvaro Cruz-Cortes,
Arturo Avendaño-Estrada,
Sarael Alcauter
et al.

Abstract: Background Glycolytic metabolism in the brain of pediatric patients, imaged with [18F]  fluorodeoxyglucose-positron emission tomography (FDG-PET) is incompletely characterized. Objective The purpose of the current study was to characterize [18F]FDG-PET brain uptake in a large sample of pediatric patients with non-central nervous system diseases as an alternative to healthy subjects to evaluate changes at different pediatric ages. … Show more

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Cited by 2 publications
(3 citation statements)
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“…During childhood development, motor, language, and visual functions gradually mature, and these functions are widely distributed in the frontal, parietal, and occipital cortices. The accelerating loss of gray-matter density may explain the metabolism decrease at the ages from 10 to 17 years ( 9 ).…”
Section: Discussionmentioning
confidence: 99%
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“…During childhood development, motor, language, and visual functions gradually mature, and these functions are widely distributed in the frontal, parietal, and occipital cortices. The accelerating loss of gray-matter density may explain the metabolism decrease at the ages from 10 to 17 years ( 9 ).…”
Section: Discussionmentioning
confidence: 99%
“…The treatment of oncology may bring potential downsides to intracranial PET results even if there are no obvious intracranial lesions. Moreover, obtaining data on PET in younger children (i.e., 0–2 years of age) is a nearly universal challenge ( 9 , 10 ). Due to factors such as growth and development in children, the PET of adults is not universally applicable, which poses considerable obstacles to pediatric brain network PET analysis.…”
Section: Introductionmentioning
confidence: 99%
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