Seminoma metastasized to the prostate: A case report and literature review

Abstract

The testicular seminomas are germ-cell tumors which account for approximately 50% of all testicular tumors. Most primary testicular germ cell tumors metastasize through a lymphatic system in a predictable pattern with the retroperitoneal lymph nodes being the most common initial metastatic site. Hematological metastasis to the distant organs is less common, and except for pulmonary metastasis, changes the classification from good to intermediate prognosis. Metastasis of testicular seminoma to the prostate is an extremely rare entity with only five reported cases in the literature. In this report, we present a 63-year-old male with recurrent testicular seminoma presenting in prostate.

A rare case of testicular mixed germ cell tumour with adrenal metastasis

“…If metastases occur beyond the lymph nodes, the lungs are commonly affected via haematogenous spread. 5 However, in our case, the pattern of spread was unusual. There were no signs of active metastasis in the retroperitoneal lymph nodes, but there was secondary localization of the seminoma to the adrenal gland.…”

A case of prostatic metastasis from non‐seminomatous testicular cancer

“…To date, 10 cases of prostatic metastasis from testicular cancer have been reported 2–11 . The pathological findings of the primary testicular lesions were seminoma and non‐seminoma in seven and three cases, respectively.…”

Metastatic Seminoma with Positive Staining of Cytokeratin and MOC31: A Diagnostic Pitfall

“…Testicular germ cell tumors are composed of seminomas and nonseminomas. Seminoma accounts for more than half of the diagnosis of germ cell tumors [ 1 ]. Most seminomas are localized to the testis, but some tend to present with lymph node metastases, mainly to the retroperitoneum [ 2 ].…”