Seminoma metastasis to the terminal ileum after a 17-year disease-free interval

Warhol, Michael J.; Nickoloff, Brian J.; Weinberg, David S.

doi:10.1002/1097-0142(19831115)52:10<1957::aid-cncr2820521030>3.0.co;2-b

Cited by 10 publications

(2 citation statements)

References 6 publications

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“…Apart from the necropsy study cited above, we are aware of only two other cases of metastatic pure seminoma of the GI tract, one involving the stomachi5 and one the terminal ileum. 16 As with our patient, both patients developed very late relapses of seminoma after a disease-free interval of 8 years and 17 years in a fashion similar to our patient.…”

Section: (269%)'supporting

confidence: 86%

Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis

Sweetenham

Whitehouse

Williams

et al. 1988

Cancer

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Six cases of metastatic germ cell tumors of the testis involving the gastrointestinal (GI) tract are reported. Three cases were primary seminomas, and three were nonseminomatous. All six cases involved the upper GI tract, three occurring at presentation and three at relapse, with a disease-free interval of 3 months to 10 years. Isolated GI involvement did not occur. The presumed mode of spread was by haematogenous dissemination in three and direct extension from paraaortic lymph nodes in three. Symptoms suggestive of involvement were severe abdominal pain secondary to high intestinal obstruction or mucosal ulceration, severe lumbar pain, and symptoms of anemia as a result of clinically evident or occult blood loss. Four patients were now disease-free after chemotherapy, one died of an unrelated illness, and one patient was receiving treatment for relapsing disease.

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Section: (269%)'supporting

confidence: 86%

Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis

Sweetenham

Whitehouse

Williams

et al. 1988

Cancer

View full text Add to dashboard Cite

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“…2, 3 The incidence of infraclavicular primary tumors reported in the literature is shown in Table 2 2–4. Metastatic testicular seminomas have been reported in diverse organs, including the retroperitoneum and intraperitoneum,5 pancreas,6 stomach,7 duodenum,8 terminal ileum,9 kidney,10 ureter,11 cervical lymph node,12 palatine tonsil,13 cervicothoracic spine,14 sphenoid sinus,15 pericardium,16 orbit,17 temporal bone,18 jaws,19 thyroid,20 and vertebral extradura 21…”

Section: Discussionmentioning

confidence: 99%