Seminoma and sertolioma in a male pseudohermaphrodite dog with unilateral cryptorchidism: short communication

Abstract

A male miniature Schnauzer with cryptorchidism and a mass growth in the right inguinal canal was admitted to the clinical center of a veterinary hospital. During surgical resection of the mass, tubular formations were found, connecting the mass to the left testicle. Histopathology revealed that the tubular formations were uterine tubes and the mass was a seminoma associated with a sertolioma of the right testicle. Further analysis also showed atrophy of the left testicle. Cytogenetic evaluation revealed normal chromosomes of male gender, 78, XY, which led to the conclusion that this was a male pseudohermaphrodite.

Seminoma and sertolioma in non-cryptorchid dog – case report

“…Sertoliomas originate from support cells located in seminiferous tubules, being the third most common neoplasm in males of the canine species, with reports in other species as well. They occur more frequently in cryptorchid animals, unilaterally, and may be bilateral in cases of bilateral cryptorchidism (COSTA, 2016;GRIECO et al, 2008;MADUREIRA et al, 2017) in contrast to that described in this report. Around 24% to 57% of animals affected by sertolioma have a hormonal imbalance, developing hyperestrogenism, resulting in paraneoplastic feminization syndrome.…”

“…Around 24% to 57% of animals affected by sertolioma have a hormonal imbalance, developing hyperestrogenism, resulting in paraneoplastic feminization syndrome. The most common clinical signs are apathy, depression, gynecomastia, alopecia, contralateral testicular atrophy, hypopigmentation, penile atrophy, pendulous foreskin, prostatic cysts and abscesses and even granulocytic anemia and thrombocytopenia (CIAPUTA et al, 2012;MADUREIRA et al, 2017;MARQUES et al, 2020). However, the animal in this report did not present any of these clinical signs.…”