Widespread use of a variety of pesticides has led to their occurrence in both surface and groundwaters. The occurrence and distribution of pesticides in the environment are closely related to their use and are determined by a series of pesticide transport and transformation processes. The occurrence and use of pesticides follow extremely complex and dynamic patterns that are affected by numerous factors related to pesticide properties, pesticide use, hydrology, and agricultural activities. The physical, chemical, and biological properties of pesticides affect their occurrence and distribution directly by altering their environmental persistence, mobility, and other fundamental transport processes. The way pesticides are used includes application amount, frequency, timing, and method has significant effects on pesticide occurrence and distribution. The quantity and frequency of application determine the overall exposure level of pesticides released into the environment, and the timing and method of application primarily change their environmental pathways and thus their occurrence as well as spatial and temporal distributions. Clearly, surface and groundwater systems have dissimilar patterns of pesticide use and occurrence due to their distinct hydrologic characteristics. The relationship of pesticide use and occurrence also varies with pesticide‐treated crops and agricultural management practices.