Semi-Automated Microfluidic Device Combined with a MiniPCR-Duplex Lateral Flow Dipstick for Screening and Visual Species Identification of Lymphatic Filariae
Abstract:Lymphatic filariasis (LF) is a leading cause of permanent disability worldwide that has been listed as a neglected tropical disease by the World Health Organization. Significant progress made by the Global Program to Eliminate Lymphatic Filariasis (GPELF) has led to a substantial decline in the population of the worm that causes LF infection. Diagnostic assays capable of detecting low levels of parasite presence are needed to diagnose LF. There is also a need for new tools that can be used in areas where multi… Show more
“…In vivo study results show that HDACi-loaded CAM effectively reduce renal inflammation and relieve. Acharya Phuakrod et al [ 15 ] apply their previously developed semi-automated microfluidic device in combination with our recently developed mini polymerase chain reaction (miniPCR) with a duplex lateral flow dipstick (DLFD) (miniPCR-DLFD) for rapid mass screening and visual species identification of lymphatic filariae in human blood. In the study, the researchers use 20 human blood samples tested positive for Malayi microfilariae, 14 human blood samples tested positive for Bancroftian microfilariae, and 100 human blood samples tested negative for mf.…”
Micro and smart devices and systems are small, interconnected devices and systems that are designed to be highly functional, efficient, and convenient [...]
“…In vivo study results show that HDACi-loaded CAM effectively reduce renal inflammation and relieve. Acharya Phuakrod et al [ 15 ] apply their previously developed semi-automated microfluidic device in combination with our recently developed mini polymerase chain reaction (miniPCR) with a duplex lateral flow dipstick (DLFD) (miniPCR-DLFD) for rapid mass screening and visual species identification of lymphatic filariae in human blood. In the study, the researchers use 20 human blood samples tested positive for Malayi microfilariae, 14 human blood samples tested positive for Bancroftian microfilariae, and 100 human blood samples tested negative for mf.…”
Micro and smart devices and systems are small, interconnected devices and systems that are designed to be highly functional, efficient, and convenient [...]
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