SEM Studies of Saponin Silver Nanoparticles Isolated From Leaves of Chenopodium album L. for In Vitro Anti-acne Activity

Choudhary, Monika; Singhal, G. S.; Bhagyawant, Sameer Suresh

doi:10.1007/s40011-019-01100-1

Cited by 11 publications

(6 citation statements)

References 18 publications

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“…Green synthesis method was found to be more efficient than the chemical reduction method because starch capping effect caused difficulties in promoting lager size nanoparticles, so the growth of smaller size nanoparticles was favored. Surface morphology of the Ag–NPs loaded PVA films have shown that nanoparticles were evenly distributed in PVA films at 3% loading, but a slight clustering of nanoparticles was observed at higher concentration, i.e., 5% Ag–NPs [ 64 , 65 , 66 ].…”

Section: Resultsmentioning

confidence: 99%

Starch-Capped Silver Nanoparticles Impregnated into Propylamine-Substituted PVA Films with Improved Antibacterial and Mechanical Properties for Wound-Bandage Applications

et al. 2020

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This research endeavor aims to develop polyvinyl alcohol (PVA) based films capable of blends with silver nanoparticles (Ag–NPs) for improved antibacterial properties and good mechanical strength to widen its scope in the field of wound dressing and bandages. This study reports synthesis of propylamine-substituted PVA (PA–PVA), Ag–NPs via chemical and green methods (starch capping) and their blended films in various proportions. Employment of starch-capped Ag–NPs as nanofillers into PVA films has substantially improved the above-mentioned properties in the ensuing nanocomposites. Synthesis of PA–PVA, starch-capped Ag–NPs and blended films were well corroborated with UV/Vis spectroscopy, FTIR, NMR, XRD and SEM analysis. Synthesized Ag–NPs were of particle shape and have an average size 20 nm and 40 nm via green and chemical synthesis, respectively. The successful blending of Ag–NPs was yielded up to five weight per weight into PA–PVA film as beyond this self-agglomeration of Ag–NPs was observed. Antibacterial assay has shown good antimicrobial activities by five weight per weight Ag–NPs(G)-encapsulated into PA–PVA blended film, i.e., 13 mm zone inhibition against Escherichia coli and 11 mm zone inhibition against Staphylococcus aureus. Physical strength was measured in the terms of young’s modulus via tensile stress–strain curves of blended films. The five weight per weight Ag–NPs(G)/PA–PVA blend film showed maximum tensile strength 168.2 MPa while three weight per weight Ag–NPs(G)/PVA blend film showed highest values for ultimate strain 297.0%. Ag–NPs embedment into PA–PVA was resulted in strong and ductile film blend than pristine PA–PVA film due to an increase in hydrogen bonding. These good results of five weight per weight Ag–NPs(G)/PA–PVA product make it a potent candidate for wound dressing application in physically active body areas.

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Section: Resultsmentioning

confidence: 99%

Starch-Capped Silver Nanoparticles Impregnated into Propylamine-Substituted PVA Films with Improved Antibacterial and Mechanical Properties for Wound-Bandage Applications

et al. 2020

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“…During synthesis of nanoparticles specific color change is observed (46). In the present study, the formation of AgNPs was observed by monitoring the change of color.…”

Section: Green Synthesis Of Saponin Conjugated Agnpsmentioning

confidence: 71%

Antioxidative properties of isolated saponins of Verbesina encelioides (Cav.) Benth. & Hook. fil ex Gray and SEM studies of synthesized green nanoparticles for acne management

Verma

Chaudhary

2019

Plant Sci. Today

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Acne is one of the most common and chronic skin problems in most adolescents and young adults due to several internal and external factors. The present study emphasizes on screening of high antioxidant potential of wild sunflower for acne therapy, as it also plays a major role in the patho-physiology of acne. The anti-oxidant potential of extracted plant compounds was carried out by using 1, 1-diphenyl-2-picryl hydrazyl (DPPH) and ferric reducing antioxidant power (FRAP). In recent years, scientists have been involved in the application of green nanoparticle synthesis. Further synthesized green nanoparticles were checked for antiacne potential. Isolated saponins and their synthesized nonolparticles would play an important role to control the acne.

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“…This peak may shift or change in intensity after the synthesis of AgNPs, as the carbonyl groups can be involved in the reduction or capping process. For example, carboxylic acids can donate electrons to silver ions and form carboxylate groups that bind to the surface of AgNPs [ 58 ]. The O-H stretching vibration of alcohols or phenols is usually seen around 3400 cm −1 and indicates the presence of hydroxyl groups (O-H) in saponins.…”

Section: Discussionmentioning

confidence: 99%

Saponin-Derived Silver Nanoparticles from Phoenix dactylifera (Ajwa Dates) Exhibit Broad-Spectrum Bioactivities Combating Bacterial Infections

Adnan,

Siddiqui,

Ashraf

et al. 2023

Antibiotics

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The emergence of antibiotic resistance poses a serious threat to humankind, emphasizing the need for alternative antimicrobial agents. This study focuses on investigating the antibacterial, antibiofilm, and anti-quorum-sensing (anti-QS) activities of saponin-derived silver nanoparticles (AgNPs-S) obtained from Ajwa dates (Phoenix dactylifera L.). The design and synthesis of these novel nanoparticles were explored in the context of developing alternative strategies to combat bacterial infections. The Ajwa date saponin extract was used as a reducing and stabilizing agent to synthesize AgNPs-S, which was characterized using various analytical techniques, including UV–Vis spectroscopy, Fourier transform infrared (FTIR) spectroscopy, and transmission electron microscopy (TEM). The biosynthesized AgNPs-S exhibited potent antibacterial activity against both Gram-positive and Gram-negative bacteria due to their capability to disrupt bacterial cell membranes and the leakage of nucleic acid and protein contents. The AgNPs-S effectively inhibited biofilm formation and quorum-sensing (QS) activity by interfering with QS signaling molecules, which play a pivotal role in bacterial virulence and pathogenicity. Furthermore, the AgNPs-S demonstrated significant antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and cytotoxicity against small lung cancer cells (A549 cells). Overall, the findings of the present study provide valuable insights into the potential use of these nanoparticles as alternative therapeutic agents for the design and development of novel antibiotics. Further investigations are warranted to elucidate the possible mechanism involved and safety concerns when it is used in vivo, paving the way for future therapeutic applications in combating bacterial infections and overcoming antibiotic resistance.

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SEM Studies of Saponin Silver Nanoparticles Isolated From Leaves of Chenopodium album L. for In Vitro Anti-acne Activity

Cited by 11 publications

References 18 publications

Starch-Capped Silver Nanoparticles Impregnated into Propylamine-Substituted PVA Films with Improved Antibacterial and Mechanical Properties for Wound-Bandage Applications

Starch-Capped Silver Nanoparticles Impregnated into Propylamine-Substituted PVA Films with Improved Antibacterial and Mechanical Properties for Wound-Bandage Applications

Antioxidative properties of isolated saponins of Verbesina encelioides (Cav.) Benth. & Hook. fil ex Gray and SEM studies of synthesized green nanoparticles for acne management

Saponin-Derived Silver Nanoparticles from Phoenix dactylifera (Ajwa Dates) Exhibit Broad-Spectrum Bioactivities Combating Bacterial Infections

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