Self-testing for Trichomonas vaginalis at home using a point-of-care test by women who request kits via the Internet

Gaydos, Charlotte A.; Jett-Goheen, Mary; Barnes, Mathilda; Dize, Laura; Hsieh, Yu Hsiang

doi:10.1071/sh16049

Cited by 11 publications

(14 citation statements)

References 4 publications

(4 reference statements)

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“…Additionally, women have been enrolled in a research study to perform the OSOM assay themselves at home after ordering a home TV test kit via the internet; they obtained accurate results compared with a mailed-in NAAT assay and found the home test to be highly acceptable 30. Use of this assay as a standard of care POC test for the detection of trichomoniasis in an emergency department was also shown to prevent overtreatment of vaginal infections compared with historical controls before the introduction of the POC test, resulting in good antibiotic stewardship 31…”

Section: Methodsmentioning

confidence: 99%

Rapid and point-of-care tests for the diagnosis ofTrichomonas vaginalisin women and men

et al. 2017

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Background Trichomonasvaginalis (TV) is a highly prevalent parasitic infection worldwide. It is associated with many adverse reproductive health outcomes. Many infections are asymptomatic and syndromic management leads to underdetection of TV. Traditional methods of TV detection such as wet preparation are insensitive. New rapid, point-of-care (POC) tests can enhance the diagnosis of trichomoniasis. Methods The authors reviewed the literature and discuss older POC tests for TV detection, as well as the OSOM lateral flow test, the AmpliVue test, the Solana test and the GeneXpert test as well as the limitations of wet preparation and culture for detection of TV. Results The OSOM test is easy to perform, compared with other POC tests, and is Clinical Laboratory Improvement Amendments (CLIA)-waived, equipment-free, has sensitivities of 83%–86% compared with nucleic acid amplification tests (NAATs) and can be performed in 15 min. The AmpliVue and the Solana tests are not CLIA waived and require small pieces of equipment. They are molecular amplified assays and can be completed in <1 hour. AmpliVue demonstrated a sensitivity for vaginal swabs of 100% compared with wet preparation/culture and 90.7% compared with NAATs. Solana demonstrated a sensitivity of 98.6%–100% for vaginal swabs and 92.9%–98% for female urines, compared with wet preparation/culture. Compared with other NAATs, the sensitivity for Solana was 89.7% for swabs and 100% for urine. The GeneXpert TV test for women and men is a moderately complex test, requires a small platform and can be performed in <1 hour. The sensitivity compared with wet preparation/culture for self-collected vaginal swabs was 96.4%, 98.9% for endocervical specimens and 98.4% for female urine. For men, sensitivity for urines was excellent (97.2%). The specificity for all assays was excellent. Conclusions Several rapid POC tests have the potential to rapidly diagnose trichomoniasis in women and one is available for detection of TV in men.

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Section: Methodsmentioning

confidence: 99%

Rapid and point-of-care tests for the diagnosis ofTrichomonas vaginalisin women and men

et al. 2017

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“…Although STIs are most prevalent in people aged 16-29 years, recent studies have suggested an increased rate in people over 30 years [25]. Furthermore, despite the finding that people who met partners on dating websites and apps were more likely to have had an STI test in the last year, a substantial proportion of respondents who reported having sex with someone they met online (likely to be a new sexual partner) reported not having an STI test in the past year, suggesting an opportunity to raise awareness about STI testing further and to use targeted advertisements to direct people to easy access points such as new websites where pathology request forms can be downloaded without attending a clinic [26]. Some have also suggested that these platforms have the capacity to enable partner notification and data collection in relation to sexual health [27].…”

Section: Discussionmentioning

confidence: 99%

Meeting Sexual Partners Through Internet Sites and Smartphone Apps in Australia: National Representative Study

Smith¹,

Guy²,

Degenhardt³

et al. 2018

J Med Internet Res

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“…12 However, the performance and acceptability of selfcollecting genital samples are high. 9,[13][14][15][16][17][18][19][20] Women report self-collection of vaginal samples to be easy and convenient, both in the clinical setting and at home and women are likely to choose self-collected vaginal swabs over sample collection during a pelvic exam. [13][14][15]20 Reports comparing self-collected penile swabs to first catch urine collected at home or in the clinic have shown self-collected penile swabs performance is equal to or better than first catch urine.…”

Section: Discussionmentioning

confidence: 99%

“…9,[13][14][15][16][17][18][19][20] Women report self-collection of vaginal samples to be easy and convenient, both in the clinical setting and at home and women are likely to choose self-collected vaginal swabs over sample collection during a pelvic exam. [13][14][15]20 Reports comparing self-collected penile swabs to first catch urine collected at home or in the clinic have shown self-collected penile swabs performance is equal to or better than first catch urine. 16,17 A recent comparison of self-collected glans/meatal dry swabs, clinician-collected urethral swabs, and first catch urine for CT/GC testing showed that selfcollected glans/meatal dry specimens had a high agreement with clinician-collected specimens and sensitivity and specificity adequate for use in screening programs.…”

Section: Discussionmentioning

confidence: 99%

Acceptability and feasibility of self-sampling for the screening of sexually transmitted infections in cabana privacy shelters

et al. 2017

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Screening for sexually transmitted infections (STIs) outside of traditional health-care facilities is limited by the privacy needed for sample collection. We explored the acceptability of privacy shelters for the self-collection of genital swabs and tested the use of privacy shelters during mobile STI screening. Attendees ≥14 years old at two outdoor community events completed a questionnaire that assessed participant characteristics, health-care access, and rating of acceptability of self-collecting penile or vaginal swabs in a privacy shelter and four other private spaces: portable restroom, health van, home, and doctor's office. A privacy shelter was used during mobile STI screening. The majority (65%) of the 95 participants reported that using a privacy shelter was somewhat or very acceptable. No participant characteristics or health-care access factors were associated with the acceptability of privacy shelters. Women rated a privacy shelter more acceptable than a portable restroom or health van. Men rated a privacy shelter more acceptable than a portable restroom. During mobile STI screening, all 13 men and women who requested STI testing used the privacy shelter for self-sampling. Rating of acceptability before and after privacy shelter use was the same. Privacy shelters may enable STI screening without using a building or vehicle for sample collection.

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Self-testing for Trichomonas vaginalis at home using a point-of-care test by women who request kits via the Internet

Cited by 11 publications

References 4 publications

Rapid and point-of-care tests for the diagnosis ofTrichomonas vaginalisin women and men

Rapid and point-of-care tests for the diagnosis ofTrichomonas vaginalisin women and men

Meeting Sexual Partners Through Internet Sites and Smartphone Apps in Australia: National Representative Study

Acceptability and feasibility of self-sampling for the screening of sexually transmitted infections in cabana privacy shelters

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