Self-reporting of hearing loss and tinnitus in the diagnosis of ototoxicity by meglumine antimoniate in patients treated for American tegumentary Leishmaniasis
Claudia Cristina Jardim Duarte,
Tania Salgado de Sousa Torraca,
Débora de Oliveira Bezerra
et al.
Abstract:Introduction
American Tegumentary Leishmaniasis (ATL) treatment is based on pentavalent antimonials (Sb5+), but these drugs have been associated to several adverse effects. Hearing loss and tinnitus during treatment with meglumine antimoniate (MA) have already been reported. This study aimed to describe the usefulness of self-reporting of hearing loss and tinnitus in diagnosing MA-induced ototoxicity.
Methods
A prospective longitudinal study was conducted with 102 patients with parasitological diagnosis of A… Show more
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