Abstract:Diabetes mellitus is closely related to oral health. We aimed to determine the relationship between diabetes mellitus and tooth extraction due to periodontal disease and dental caries. Japan’s second nationwide survey data collected from 4 June to 10 June 2018 was used to identify reasons for tooth extraction among patients aged > 40 years. General dentists collected information on patients who underwent tooth extraction procedures, and the presence of diabetes mellitus was determined through interviews. Mu… Show more
“…Participants who answered "yes" were identified as self-reported diabetics, and the others were not self-reported diabetics. [9][10][11] Participants with fasting blood glucose ≥126 mg/dL (7.0 mmol/L) or glycosylated hemoglobin ≥6.5% were considered to be bio-assayed diabetics. Both self-reported and bio-assayed diabetics were considered to be diabetics.…”
Diabetes seriously affects the health of middle-aged and elderly. What we can do is to suppress the progression and avoid complications of diabetes. The aim of this study was to evaluate the prevalence, management and influencing factors in middle-aged and elderly diabetics. The data used in our study came from the follow-up survey (2015) of China Health and Retirement Longitudinal Study. After all the questionnaire data of participants was acquired, the first screening step was conducted and the participants without blood glucose or glycosylated hemoglobin test results were excluded. In the second screening step, participants without self-reported diabetes, age <45 were excluded. After data screening, STATA 16.0 software (StataCorp, USA) was used to conduct statistical analysis. Multiple logistics regression was used to analyze the influencing factors of diabetes in middle-aged and elderly. After data screening, A total of 9738 participants were enrolled in the survey of the China Health and Retirement Longitudinal Study in 2015, including diabetes 1965 and control 7773. The prevalence of diabetes in age >60 (22.20%) was significantly higher than that in age 45 to 60 (16.60%). Age, residence, physical activity, drinking, smoking and body mass index were key influencing factors according to the results of logistics regression. 46.92% diabetics were diagnosed in hospital, 22.14% were diagnosed by community medical care. 1298 among 1965 diabetes patients had standardized medication to control blood glucose, the rate was only 66.01%. The awareness rate of diabetes was only 28.75%, and the monitoring, treatment and accepting medical advice rates were 68.32%, 66.01% and 56.99% separately. The follow-up rate of diabetes was only 14.16%. Diabetes is widely prevalent in the middle-aged and elderly with the prevalence of 16.60% in the participants with age 45 to 60. The rate of self-rated diabetics underestimated the true prevalence of diabetes. Age, residence, physical activity, drinking, smoking and body mass index are key influencing factors to diabetes. Although a national diabetes health management model has been established, the awareness of diabetes was only 28.75%. Standardized diabetes registration and regular follow up should also be strictly implemented.
“…Participants who answered "yes" were identified as self-reported diabetics, and the others were not self-reported diabetics. [9][10][11] Participants with fasting blood glucose ≥126 mg/dL (7.0 mmol/L) or glycosylated hemoglobin ≥6.5% were considered to be bio-assayed diabetics. Both self-reported and bio-assayed diabetics were considered to be diabetics.…”
Diabetes seriously affects the health of middle-aged and elderly. What we can do is to suppress the progression and avoid complications of diabetes. The aim of this study was to evaluate the prevalence, management and influencing factors in middle-aged and elderly diabetics. The data used in our study came from the follow-up survey (2015) of China Health and Retirement Longitudinal Study. After all the questionnaire data of participants was acquired, the first screening step was conducted and the participants without blood glucose or glycosylated hemoglobin test results were excluded. In the second screening step, participants without self-reported diabetes, age <45 were excluded. After data screening, STATA 16.0 software (StataCorp, USA) was used to conduct statistical analysis. Multiple logistics regression was used to analyze the influencing factors of diabetes in middle-aged and elderly. After data screening, A total of 9738 participants were enrolled in the survey of the China Health and Retirement Longitudinal Study in 2015, including diabetes 1965 and control 7773. The prevalence of diabetes in age >60 (22.20%) was significantly higher than that in age 45 to 60 (16.60%). Age, residence, physical activity, drinking, smoking and body mass index were key influencing factors according to the results of logistics regression. 46.92% diabetics were diagnosed in hospital, 22.14% were diagnosed by community medical care. 1298 among 1965 diabetes patients had standardized medication to control blood glucose, the rate was only 66.01%. The awareness rate of diabetes was only 28.75%, and the monitoring, treatment and accepting medical advice rates were 68.32%, 66.01% and 56.99% separately. The follow-up rate of diabetes was only 14.16%. Diabetes is widely prevalent in the middle-aged and elderly with the prevalence of 16.60% in the participants with age 45 to 60. The rate of self-rated diabetics underestimated the true prevalence of diabetes. Age, residence, physical activity, drinking, smoking and body mass index are key influencing factors to diabetes. Although a national diabetes health management model has been established, the awareness of diabetes was only 28.75%. Standardized diabetes registration and regular follow up should also be strictly implemented.
“…Factors associated with the use of dental services in diabetic people (Andrea Petricia Ramirez Ortega) 529 with diabetes mellitus are dental caries, gingivitis, and periodontitis [11], [12]. Several studies have identified the relationship between diabetes and periodontal diseases by observing advanced periodontitis in patients with type 2 diabetes mellitus (DM2) and high levels of glycosylated hemoglobin (HbA1c) [13]- [15].…”
The use of dental services prevents oral diseases where its prevalence is associated with chronic diseases such as diabetes mellitus (DM) that also has increased risks with age. Therefore, this observational, analytical and crosssectional study was conducted among 3,882 people. Data used for analysis in this research was collected from the Demographic and Family Health Survey of Peru (ENDES) from 2019 to 2021. Results from poisson regression analysis showed female gender had 1.02 times the probability of going to the dental service; likewise, people who were 91 to 100 years old had 12% more, the probability, like those with secondary education, had 8% more and those with the highest average, richest and richest wealth index had 20% more, 29% more and 29% more, respectively, the probability of going to the dental health service, as opposed to those who were very poor. The study concluded that there are several sociodemographic factors (such as being female, age progressed, natural region, those with high school, wealth index, type of residence) and personal factors (history of hypertension (HTN), physical disability) associated with a lack of access to dental services in people over 60 years old.
“… 7 In clinical settings, T2DM and periodontal diseases have a positive correlation. 8 , 9 Patients with more severe diabetes tend to have more serious periodontal diseases and vice versa. Therefore, the histopathological examination of periodontal tissue changes is very significant in the early diagnosis of periodontal diseases induced by diabetes.…”
Implications of lysyl oxidaselike protein 3 expression in the periodontium of diabetic rats Objectives: Diabetes has been strongly associated with periodontal diseases. The periodontal ligament (PDL) has an abundant extracellular matrix (ECM). Lysyl oxidases (LOXs) are closely associated with various diseases caused by abnormal ECM functions, however, the role of LOXs in periodontal diseases induced by diabetes remains unclear. Methodology: In this study, 8-week-old Zucker diabetic fatty rats were used to establish a type 2 diabetes mellitus (T2DM) model. After 9 and 16 weeks, hematoxylin and eosin (H&E), Masson's trichrome, and immunohistochemical staining were performed. Results: After 9 weeks, loose collagen fibers were found in the interradicular area of the diabetic group, in opposition to the control group.There were no significant differences in LOX expression between the diabetic and control groups (p>0.05). However, after 16 weeks, the diabetic group presented a disordered arrangement of the PDL, showing decreased collagen content and significantly increased lysyl oxidase-like protein 3 (LOXL3) expression when compared with the control group (p<0.05). This suggests that LOXL3 plays a significant role in periodontal histopathological changes in diabetic rats. Conclusion: Our study showed elevated LOXL3 expression in the PDL of diabetic rats after 16 weeks, suggesting that LOXL3 may be involved in the occurrence and development of periodontal histopathological changes in diabetic rats. LOXL3 could be further used as an indicator for the early diagnosis of diabetic periodontitis in T2DM patients in clinical settings.
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