Self-ratiometric fluorescence approach based on plant extract-assisted synthesized silver nanoparticles for the determination of vanillin

El Hamd, Mohamed A.; El-Maghrabey, Mahmoud; Almawash, Saud; El-Shaheny, Rania; Magdy, Galal

doi:10.1007/s00604-023-06093-3

Cited by 10 publications

(3 citation statements)

References 38 publications

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“…The premium associated with natural ingredients and the potential health ramifications of synthetic additives further amplifies the demand for precise, reliable quantification techniques. 3,4 Addressing this need, the introduction of a tin sulfide/ carbon nanofiber (SnS/CNF) composite for use as an electrochemical sensor marks a significant shift toward sophisticated, nanomaterial-enhanced detection methods. 5,6 The synthesis of this composite capitalizes on the unique physicochemical and electrocatalytic properties of its constituent materials to optimize the electrochemical sensing interface, thereby facilitating advanced detection mechanisms.…”

Section: ■ Introductionmentioning

confidence: 99%

“…The ubiquity of vanillin in both natural and synthetic forms heightens the need for precise analytical methodologies to assess its concentration and purity in food products. , These methodologies must cater to stringent quality control, ensure authenticity, and adhere to health regulations to differentiate between naturally sourced vanillin and synthetic variants. The premium associated with natural ingredients and the potential health ramifications of synthetic additives further amplifies the demand for precise, reliable quantification techniques. , …”

Section: Introductionmentioning

confidence: 99%

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Nanoparticles of SnS on Carbon Nanofibers for Electrochemical Detection of Vanillin

Gokulkumar,

Huang,

Lee

et al. 2024

ACS Appl. Nano Mater.

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This study reports the development of a highsensitive electrochemical sensor employing a tin sulfide-carbon nanofiber (SnS/CNF) composite for the precise detection of vanillin in food products. Utilizing the synergistic properties of SnS nanoparticles and CNFs�namely, superior electrocatalytic properties and enhanced electrical conductivity�the synthesized SnS/ CNF composite was applied to modify glassy carbon electrodes, demonstrating remarkable selectivity and sensitivity toward vanillin. Characterization of the composite affirmed its homogeneous structure, crucial for the observed electrochemical reactivity and stability. Electrochemical evaluations, including cyclic voltammetry and differential pulse voltammetry, showcased a linear response to vanillin across a wide concentration range (0.01−180.5 μM; 240.5−520.6 μM) and low limit of detection (0.021 μM) and (i−t) amperometric showcased a linear response to vanillin across a wide concentration range (0.00125−506.75 μM; 575.5−2452 μM) with an impressively low limit of detection (0.0032 μM). Further, the sensor's reliability was validated through repeatability and reproducibility assessments, alongside successful quantification of vanillin in complex matrices such as milk and cake, underscoring its applicability in food quality control. This work introduces a significant advancement in the field of electrochemical sensing, offering a sensitive, selective, and stable platform for the analysis of key flavor compounds in the food industry.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nanoparticles of SnS on Carbon Nanofibers for Electrochemical Detection of Vanillin

Gokulkumar,

Huang,

Lee

et al. 2024

ACS Appl. Nano Mater.

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“…[17][18][19][20] Many studies have aimed at developing novel nanomaterial-based sensors for applications in biology and medicine, while their clinical applications are greatly restricted by high cost and adding highly toxic components. [21][22][23] As novel nanomaterials, carbon dots (CDs) have gained particular attention in recent years owing to their outstanding characteristics and wide-ranging pharmaceutical applications. [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] In particular, their small size and large surface area make them highly water-soluble and biocompatible, which holds great promise for drug delivery.…”

Section: Introductionmentioning

confidence: 99%

Novel Carbon Dots Derived from Moutan Cortex Significantly Improve the Solubility and Bioavailability of Mangiferin

Kong,

Wang,

Sun

et al. 2024

IJN

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Background Mangiferin (MA), a bioactive C-glucosyl xanthone with a wide range of interesting therapeutic properties, has recently attracted considerable attention. However, its application in biomedicine is limited by poor solubility and bioavailability. Carbon dots (CDs), novel nanomaterials, have immense promise as carriers for improving the biopharmaceutical properties of active components because of their outstanding characteristics. Methods In this study, a novel water-soluble carbon dot (MC-CDs) was prepared for the first time from an aqueous extract of Moutan Cortex Carbonisata , and characterized by various spectroscopies, zeta potential and high-resolution transmission electron microscopy (HRTEM). The toxicity effect was investigated using the CCK-8 assay in vitro. In addition, the potential of MC-CDs as carriers for improving the pharmacokinetic parameters was evaluated in vivo. Results The results indicated that MC-CDs with a uniform spherical particle size of 1–5 nm were successfully prepared, which significantly increased the solubility of MA in water. The MC-CDs exhibited low toxicity in HT-22 cells. Most importantly, the MC-CDs effectively affected the pharmacokinetic parameters of MA in normal rats. UPLC-MS analysis indicated that the area under the maximum blood concentration of MA from mangiferin-MC-CDs (MA-MC-CDs) was 1.6-fold higher than that from the MA suspension liquid (MA control) after oral administration at a dose of 20 mg/kg. Conclusion Moutan Cortex -derived novel CDs exhibited superior performance in improving the solubility and bioavailability of MA. This study not only opens new possibilities for the future clinical application of MA but also provides evidence for the development of green biological carbon dots as a drug delivery system to improve the biopharmaceutical properties of insoluble drugs.

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Picomole determination of vanillin in infant formula by molecularly imprinted polypyrrole nanowires/reduced graphene oxide-based electrochemical sensor

Feng,

Guo,

Zhang

et al. 2024

Microchemical Journal

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Self-ratiometric fluorescence approach based on plant extract-assisted synthesized silver nanoparticles for the determination of vanillin

Cited by 10 publications

References 38 publications

Nanoparticles of SnS on Carbon Nanofibers for Electrochemical Detection of Vanillin

Nanoparticles of SnS on Carbon Nanofibers for Electrochemical Detection of Vanillin

Novel Carbon Dots Derived from Moutan Cortex Significantly Improve the Solubility and Bioavailability of Mangiferin

Picomole determination of vanillin in infant formula by molecularly imprinted polypyrrole nanowires/reduced graphene oxide-based electrochemical sensor

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