2015
DOI: 10.1039/c4tb02067g
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Self-polymerization of dopamine and polyethyleneimine: novel fluorescent organic nanoprobes for biological imaging applications

Abstract: Novel fluorescent organic nanoparticles based on self-polymerization of dopamine and polyethyleneimine were prepared and utilized for biological imaging applications.

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Cited by 268 publications
(106 citation statements)
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“…[1][2][3][4][5][6][7][8][9] Especially fluorescent organic nanoparticles (FONs) have aroused considerable interest in biological applications because of their biocompatibility, rich chemical modification, biodegradability, and high fluorescence quantum yield (FQY). [10][11][12][13][14][15] FONs, such as fluorescent macromolecules, fluorescent polymeric nanoparticles, and fluorescent supermacromolecular nanoassemblies, have been modified for further conjugation with biomolecules and/or fluorophores. [16,17] Methods such as living radical polymerization (LRP) to form core-shell structures or attaching fluorescent dyes in polymeric spheres have been reported.…”
Section: Introductionmentioning
confidence: 99%
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“…[1][2][3][4][5][6][7][8][9] Especially fluorescent organic nanoparticles (FONs) have aroused considerable interest in biological applications because of their biocompatibility, rich chemical modification, biodegradability, and high fluorescence quantum yield (FQY). [10][11][12][13][14][15] FONs, such as fluorescent macromolecules, fluorescent polymeric nanoparticles, and fluorescent supermacromolecular nanoassemblies, have been modified for further conjugation with biomolecules and/or fluorophores. [16,17] Methods such as living radical polymerization (LRP) to form core-shell structures or attaching fluorescent dyes in polymeric spheres have been reported.…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, Zhang et al [36,37] have developed a number of covalent strategies for fabrication of AIE dyes containeing amphiphilic FONs through reversible addition-fragmentation chain-transfer (RAFT) polymerization and cross-linking. [38][39][40][41][42][43][44][45][46] However, most of these strategies still have some shortcoming. For example, most of commercially available amphiphilic compounds are expensive, and the obtained nanoprobes are often not stable when the concentration is lower than the critical micelle concentration (CMC).…”
Section: Introductionmentioning
confidence: 99%
“…It is well-known that the selfpolymerization of dopamine can coat on a large number of material surfaces for the adhesion of PDA. More importantly, the PDA coatings can provide an active platform for further surface modification through different strategies including surface initiated polymerization, free radical polymerization, and Michael addition reaction [42][43][44][45][46][47][48]. In this work, the PSPSH polymer terminated with amino group was first synthesized via free radical polymerization using cysteamine hydrochloride as the chain transfer agent and SPSH as the monomer.…”
Section: Resultsmentioning
confidence: 99%
“…Previous studies have suggested that the strong adhesion of mussel is associated with the dopaminelike components in mussel foot proteins. Since the pioneer work by Lee et al in 2007, mussel inspired chemistry has attracted increasing interest and been intensively explored for a wide range of applications [31][32][33][34][35][36][37][38][39][40]. For example, Lee et al demonstrated that dopamine could self-polymerize under alkaline environment to form a polymer coating on a variety of organic and inorganic materials, including polymers, noble metals, oxides, semiconductors and ceramics [41].…”
Section: Introductionmentioning
confidence: 98%