Self‐Injurious Behavior ( SIB )

Abstract

Self‐injurious behavior (SIB) occurs in both human and nonhuman primates. Only a small percentage of monkeys develop this syndrome, which is manifested primarily as bites directed to the limbs. Monkeys with SIB show a dysregulation (blunting) of the stress response system and altered beta‐endorphin levels, and are genetically different than controls. SIB is also associated with early life stress events. Attempts to treat this condition have met with limited success. Some efficacy has been noted for both social living and outdoor housing. Some success has been achieved with pharmacotherapy, but most monkeys relapse post treatment, with the possible exception of naltrexone. Further research is needed to understand the function of this behavior in order to design more effective treatments.