Self-esteem modulates dorsal anterior cingulate cortical response in self-referential processing

Ye, Juan; Dedovic, Katarina; Chen, Weihai

doi:10.1016/j.neuropsychologia.2012.02.010

Cited by 34 publications

(26 citation statements)

References 15 publications

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“…Another previous study has also reported that activation in the anterior cingulate in response to processing of self-referential items was negatively associated with trait levels of self-esteem (Yang et al, 2012). Since the magnitude of self-esteem tends to have a greater influence in contexts where social rejection is a potential factor (Yang et al, 2012), it is possible that this is of less relevance when judging the value of possessions owned by self or others than in the more personal context of attributing positive or negative behavioral traits to self and others. We also found no evidence for a modulatory influence of SCS scores on behavioral or neural effects of OXT and so it would appear that the relative strength of collectivism compared to independent traits within our cohort of Chinese subjects was not of great importance.…”

Section: Discussionmentioning

confidence: 92%

Oxytocin Increases the Perceived Value of Both Self- and Other-Owned Items and Alters Medial Prefrontal Cortex Activity in an Endowment Task

Zhao

Geng

Luo

et al. 2017

Front. Hum. Neurosci.

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The neuropeptide oxytocin (OXT) can influence self-processing and may help motivate us to value the attributes of others in a more self-like manner by reducing medial prefrontal cortex (mPFC) responses. We do not know however whether this OXT effect extends to possessions. We tend to place a higher monetary value on specific objects that belong to us compared to others, known as the “endowment effect”. In two double-blind, between-subject placebo (PLC) controlled experiments in subjects from a collectivist culture, we investigated the influence of intranasal OXT on the endowment effect, with the second study incorporating functional magnetic resonance imaging (fMRI). In the task, subjects decided whether to buy or sell their own or others’ (mother/father/classmate/stranger) possessions at various prices. Both experiments demonstrated an endowment effect in the self-owned condition which extended to close others (mother/father) and OXT increased this for self and all other-owned items. This OXT effect was associated with reduced activity in the ventral mPFC (vmPFC) in the self-owned condition but increased in the mother-condition. For the classmate- and stranger-owned conditions OXT increased activity in the dorsal mPFC (dmPFC). Changes in vmPFC activation were associated with the size of the endowment effect for self- and mother-owned items. Functional connectivity between the dmPFC and ventral striatum (VStr) was reduced by OXT in self- and mother-owned conditions and between vmPFC and precuneus in the self-condition. Overall our results show that OXT enhances the endowment effect for both self- and other-owned items in Chinese subjects. This effect is associated with reduced mPFC activation in the self-condition but enhanced activation in all other-conditions and involves differential actions on both dorsal and ventral regions as well as functional connectivity with brain reward and other self-processing regions. Overall our findings suggest that OXT increases the perceived value of both self- and other-owned items by acting on neural circuitry involved in self-processing and reward.

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Section: Discussionmentioning

confidence: 92%

Oxytocin Increases the Perceived Value of Both Self- and Other-Owned Items and Alters Medial Prefrontal Cortex Activity in an Endowment Task

Zhao

Geng

Luo

et al. 2017

Front. Hum. Neurosci.

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“…Interestingly, our findings showed that despite OXT reducing mPFC activation in self and other trait judgments, it also resulted in a significantly greater association between dmPFC activity and both reaction times for trait‐judgments and SES scores. The mPFC has been shown to be engaged during tasks which require making specific judgments about both one's own traits and those of others' [Cikara et al, ; Kim and Johnson, ; Yang et al, ]. Thus, despite mainly reducing activation changes OXT might at the same time be reducing noise in this neural system, thereby revealing a closer association with both RTs and behavioral traits.…”

Section: Discussionmentioning

confidence: 99%

Oxytocin blurs the self-other distinction during trait judgments and reduces medial prefrontal cortex responses

Zhao

Yao

et al. 2016

Hum. Brain Mapp.

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The neuropeptide oxytocin (OXT) may act either to increase or blur the distinction between self and other and thereby promote either more selfish or altruistic behaviors. To attempt to distinguish between these two possibilities we performed a double-blind, between-subject, placebo-controlled design study to investigate the effect of intranasal OXT on self and other (mother, classmate, or stranger) trait judgments in conjunction with functional magnetic resonance imaging. Results showed that OXT reduced response times for making both self and other judgments, but also reduced the accuracy of their subsequent recall, thereby abolishing the normal self-bias observed in this task. OXT also abolished the positive correlation between response and self-esteem scale scores seen in the PLC group, suggesting that its effects were strongest in individuals with higher levels of self-esteem. A whole-brain functional magnetic resonance imaging analysis revealed that OXT also reduced responses during both self and other trait judgments in the dorsal (dmPFC) and ventral (vmPFC) medial prefrontal cortex. A subsequent region of interest analysis revealed that behavioral performance and self-esteem scale scores were associated with dmPFC activation and its functional connectivity with the anterior cingulate and between the vmPFC and posterior cingulate. Thus overall, while OXT may improve speed of decision making in self -vs. other trait judgments it also blunts the normal bias towards remembering self-attributes and reduces mPFC responses and connectivity with other cortical midline regions involved in self-processing. This is consistent with the view that OXT can reduce self-centered behavior. Hum Brain Mapp 37:2512-2527, 2016. © 2016 Wiley Periodicals, Inc.

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“…Previous ERP studies have also found that individuals with low self-esteem tend to easily direct their attention to emotional stimuli, such as social rejection and negatively self-relevant stimuli, and demonstrated enhanced P2 amplitudes or prolonged P2 latencies for processing these emotion-related stimuli (Li et al, 2012;Yang et al, 2012Yang et al, , 2014Li and Yang, 2013;Zhang et al, 2013). Consistent with these studies, the present study found that individuals with low self-esteem demonstrated larger P2 amplitudes in response to their own names than to close others' names, but individuals with high self-esteem did not show such effect.…”

Section: Discussionmentioning

confidence: 99%

Self-esteem modulates automatic attentional responses to self-relevant stimuli: evidence from event-related brain potentials

Chen

Shui

Zhong

2015

Front. Hum. Neurosci.

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Previous studies have widely shown that self-esteem modulates the attention bias towards social rejection or emotion-related information. However, little is known about the influences of self-esteem on attention bias towards self-relevant stimuli. We aimed to investigate neural correlates that underlie the modulation effect of self-esteem on self-relevant processing. Event-related potentials (ERP) were recorded for subjects' own names and close others' names (the names of their friends) while subjects performed a three-stimulus oddball task. The results showed larger P2 amplitudes for one's own name than for close-other's name in the low self-esteem group, whereas this P2 effect were not observed in the high self-esteem group. In addition, one's own name elicited equivalent N250 amplitudes and larger P3 amplitudes compared with close-other's name in both high and low self-esteem groups. However, no interaction effects were observed between self-esteem and self-relevant processing in the N250 and P3 components. Thus, we found that the modulation effects of self-esteem on self-relevant processing occurred at the early P2 stage, but not at the later N250 and P3 stages. These findings reflect that individuals with low self-esteem demonstrate automatic attention towards their own names.

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Self-esteem modulates dorsal anterior cingulate cortical response in self-referential processing

Cited by 34 publications

References 15 publications

Oxytocin Increases the Perceived Value of Both Self- and Other-Owned Items and Alters Medial Prefrontal Cortex Activity in an Endowment Task

Oxytocin Increases the Perceived Value of Both Self- and Other-Owned Items and Alters Medial Prefrontal Cortex Activity in an Endowment Task

Oxytocin blurs the self-other distinction during trait judgments and reduces medial prefrontal cortex responses

Self-esteem modulates automatic attentional responses to self-relevant stimuli: evidence from event-related brain potentials

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