Self-Enhanced Antibacterial and Antifouling Behavior of Three-Dimensional Porous Cu<sub>2</sub>O Nanoparticles Functionalized by an Organic–Inorganic Hybrid Matrix

Li, Huali; Zhang, Liuqin; Zhang, Xiaohu; Zhu, Guangyu; Zheng, Dongchen; Luo, Shuwen; Wu, Min; Li, Weihua; Liu, Fa‐Qian

doi:10.1021/acsami.3c06905

Cited by 7 publications

(2 citation statements)

References 57 publications

(95 reference statements)

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“…Furthermore, the Cu 2 O spectrum showed that the strong characteristic peaks symbolizing Cu + 2p 3/2 and Cu + 2p 1/2 were located at 932.38 and 952.38 eV, whereas the characteristic peaks symbolizing Cu ion 2p 3/2 and Cu ion 2p 1/2 were located at 934.68 and 955.08 eV, respectively [ 39 ]. As a comparison, both peak positions symbolizing Cu + in Cu 2 O@rGO redshifted, which indicates that there is an interaction between rGO and Cu 2 O [ 40 ]. Based on previous studies, a reasonable explanation is that Cu + utilized oxygen-containing functional groups of rGO as targets for the in situ growth of Cu 2 O [ 41 , 42 ].…”

Section: Resultsmentioning

confidence: 99%

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

He,

Zan,

et al. 2024

Nanomaterials

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Cuprous oxide (Cu2O) has great potential in photodynamic therapy for implant-associated infections due to its good biocompatibility and photoelectric properties. Nevertheless, the rapid recombination of electrons and holes weakens its photodynamic antibacterial effect. In this work, a new nanosystem (Cu2O@rGO) with excellent photodynamic performance was designed via the in situ growth of Cu2O on reduced graphene oxide (rGO). Specifically, rGO with lower Fermi levels served as an electron trap to capture photoexcited electrons from Cu2O, thereby promoting electron-hole separation. More importantly, the surface of rGO could quickly transfer electrons from Cu2O owing to its excellent conductivity, thus efficiently suppressing the recombination of electron-hole pairs. Subsequently, the Cu2O@rGO nanoparticle was introduced into poly-L-lactic acid (PLLA) powder to prepare PLLA/Cu2O@rGO porous scaffolds through selective laser sintering. Photochemical analysis showed that the photocurrent of Cu2O@rGO increased by about two times after the incorporation of GO nanosheets, thus enhancing the efficiency of photogenerated charge carriers and promoting electron-hole separation. Moreover, the ROS production of the PLLA/Cu2O@rGO scaffold was significantly increased by about two times as compared with that of the PLLA/Cu2O scaffold. The antibacterial results showed that PLLA/Cu2O@rGO possessed antibacterial rates of 83.7% and 81.3% against Escherichia coli and Staphylococcus aureus, respectively. In summary, this work provides an effective strategy for combating implant-related infections.

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Section: Resultsmentioning

confidence: 99%

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

He,

Zan,

et al. 2024

Nanomaterials

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“…The initial phases of biofouling layer development involve the irreversible colonization and differentiation of bacteria on the substrate surface . Consequently, it is recommended to assess the antibacterial properties of samples prior to investigating their antibiofouling characteristics.…”

Section: Results and Discussionmentioning

confidence: 99%

MoS₂/Ag-TiO₂/Polyurethane Nanocomposite as a Photocatalytic Coating for Antibiofouling Applications

Vijayan,

Joseph,

Nair

et al. 2024

ACS Appl. Nano Mater.

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Marine biofouling continues to pose a major challenge for the maritime industries, affecting both vessels and stationary installations. Various types of antifouling coatings are being utilized on ship hulls and structures to inhibit the growth of fouling organisms. This study aims to explore the viability of employing MoS 2 /Ag-TiO 2 (MAT) incorporated polyurethane coatings on mild steel as an effective antifouling coating. MAT nanocomposites were synthesized using a liquid phase exfoliation process, and their structure and morphology were characterized using various spectroscopic and microscopic methods. The photocatalytic efficiency of the MAT nanocomposite was evaluated by measuring the degradation of crystal violet (CV) dye under sunlight, achieving an efficiency rate of 81%. Antibacterial tests on two microbial strains, Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA), revealed that the developed heterostructure had maximum photocatalytic killing activity for a concentration of 400 μg/mL for PA and 600 μg/mL for SA. Furthermore, the utilization of MAT coatings in marine structures was investigated using a marine water consortium to assess their effect on inhibiting biofilm formation. The findings demonstrated a significant reduction (∼95%) in bacterial adhesion compared to the uncoated surfaces, leading to a decrease in biofouling. Studies on microbial-induced corrosion demonstrate that MAT coatings display outstanding improvements in charge transfer resistance (4605 Ω) and coating resistance (7310 Ω) even after prolonged exposure to corrosive environments. The toxicity assessment conducted on the MAT nanocomposite toward L929 cell lines (mouse skin fibroblasts) and MG63 (human osteosarcoma) indicated an excellent biocompatibility with a cell survival rate of nearly 94% for a concentration of 400 μg/mL. This work demonstrates environment-friendly and cost-effective antibiofouling coatings employing the dual functionalities of photocatalysis and antibacterial properties of the MAT heterojunction.

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Polydopamine functionalized FeVO4@PVDF ultrafiltration membrane with superior antifouling and detoxification properties

Wei,

Naraginti,

Yang

et al. 2024

Chemical Engineering Journal

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Self-Enhanced Antibacterial and Antifouling Behavior of Three-Dimensional Porous Cu₂O Nanoparticles Functionalized by an Organic–Inorganic Hybrid Matrix

Cited by 7 publications

References 57 publications

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

MoS₂/Ag-TiO₂/Polyurethane Nanocomposite as a Photocatalytic Coating for Antibiofouling Applications

Polydopamine functionalized FeVO4@PVDF ultrafiltration membrane with superior antifouling and detoxification properties

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Self-Enhanced Antibacterial and Antifouling Behavior of Three-Dimensional Porous Cu2O Nanoparticles Functionalized by an Organic–Inorganic Hybrid Matrix

Cited by 7 publications

References 57 publications

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

A Photochemically Active Cu2O Nanoparticle Endows Scaffolds with Good Antibacterial Performance by Efficiently Generating Reactive Oxygen Species

MoS2/Ag-TiO2/Polyurethane Nanocomposite as a Photocatalytic Coating for Antibiofouling Applications

Polydopamine functionalized FeVO4@PVDF ultrafiltration membrane with superior antifouling and detoxification properties

Contact Info

Product

Resources

About

Self-Enhanced Antibacterial and Antifouling Behavior of Three-Dimensional Porous Cu₂O Nanoparticles Functionalized by an Organic–Inorganic Hybrid Matrix

MoS₂/Ag-TiO₂/Polyurethane Nanocomposite as a Photocatalytic Coating for Antibiofouling Applications