Self-assessment of somatic and psychic symptoms during a two months period of hormone replacement therapy in perimenopausal women

Validation of POMS questionnaire in postmenopausal women

“…There is a strong clinical interest in mood in this population because menopause-related vasomotor symptoms (hot flushes, night sweats) have shown an association with mood disturbances [3] and contribute to the increased risk of depression during the menopausal transition [4,5] among women with a wide range of hot flush frequencies. The POMS has been used in studies designed: to measure mood changes during the menopausal transition [6] to investigate effects of menopausal hormone therapy on mood [7][8][9], to assess effects of treatments for menopausal symptoms on mood [10][11][12][13], and to measure the effects other therapeutic interventions on mood in menopausal women [14][15][16]. However, despite the widespread reliance on this instrument, the POMS has never been validated in this population among women with frequent vasomotor symptoms.…”