Self-assembly of stimuli-responsive block copolymers in aqueous solutions: an overview

Khimani, Mehul; Patel, Hiren; Patel, Vipul M.; Parekh, Paresh; Vekariya, Rohit L.

doi:10.1007/s00289-019-03046-w

Cited by 27 publications

(16 citation statements)

References 153 publications

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“…Here, three changes in slope can be observed in the α T plot, at T = 313, 319, and 331 K. Since no cloud point transition was observed within this temperature range (Figure a), these changes are attributed to micelle or gel formation. At T = 313 K, it is possible that the critical micelle temperature (CTC) occurs . At T = 319 and 331 K, as reported for L64 + water systems, second virial coefficient calculations show a change in slope, indicating that water becomes a poorer solvent at this temperature .…”

Section: Resultsmentioning

confidence: 72%

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems

et al. 2021

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Thermophysical properties and phase behavior of seven {polymer (1) + water (2)} systems were determined using PPG 400 , Ultraric PE62, Pluronic L64, Pluronic L35, PEG 400 , PEG 600 , and PEG 1000 . Density (ρ) and refractive index (n) were measured for the whole range of w 1 at T = 293.2 K. Correlation with Redlich−Kister equation and prediction with Lorentz−Lorenz theoretical model were done. pH was measured for different mass fractions at ambient temperature (T ≈ 298.2 K). Cloud point temperature (T cloud ) was measured for different polymer mass fractions (w 1 ) from 0.02 up to 0.30. The thermal expansion coefficient (α T ) was calculated for w 1 = 0.15 and temperature (T) from 278.2 up to 348.2 K. Experiments were conducted at atmospheric pressure (P ≈ 95 kPa). The obtained thermophysical properties indicate that PEGs + water have the highest ρ while PPG 400 + water has the smallest ρ. Also, all ρ vs w 1 curves present a maximum value. n profiles are similar for all systems, showing the same refractive index increment for w 1 below 0.4. Density (Δρ) and refractive index (Δn) deviations are higher for the PPG 400 + water system, mainly due to the highest propylene content and hydrophobic character of PPG units. Moreover, pH varies with polymer mass fraction reaching a minimum value, probably because polymers release H + in solution. Phase transition results indicate that Tcloud and α T present related behaviors, i.e., when solution became turbid, α T shows an abrupt change in slope.

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Section: Resultsmentioning

confidence: 72%

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems

et al. 2021

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“…However, the application field of DHCs expanded rapidly, and this polymer class is recently used in biomedical applications, as nanocarriers and imaging/contrast agents, in catalysis, sensing, or within hybrid materials and this is also highlighted here. 12,15,33,44,48–50 Their water-solubility, together with their potential binding sites, renders DHBCs suitable organic components for hybrid materials in aqueous environments, and their combination with various inorganic materials was found to yield high performance materials. 33,51…”

Section: Introductionmentioning

confidence: 99%

Double hydrophilic copolymers – synthetic approaches, architectural variety, and current application fields

2022

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“…Amphiphilic molecules, or surfactants, can be classified as ionic or non-ionic, and both types have advantages in certain fields of application [ 6 ]. Non-ionic surfactants comprise monoglycerides [ 7 , 8 ], fatty acids [ 9 ], phospholipids [ 10 ], amphiphilic block-copolymers [ 11 , 12 , 13 , 14 , 15 , 16 ] and many other classes of molecules [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Inverse ISAsomes in Bio-Compatible Oils—Exploring Formulations in Squalane, Triolein and Olive Oil

2022

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In contrast to their more common counterparts in aqueous solutions, inverse ISAsomes (internally self-assembled somes/particles) are formulated as kinetically stabilised dispersions of hydrophilic, lyotropic liquid-crystalline (LC) phases in non-polar oils. This contribution reports on their formation in bio-compatible oils. We found that it is possible to create inverse hexosomes, inverse micellar cubosomes (Fd3m) and an inverse emulsified microemulsion (EME) in excess squalane with a polyethylene glycol alkyl ether as the primary surfactant forming the LC phase and to stabilise them with hydrophobised silica nanoparticles. Furthermore, an emulsified -phase and inverse hexosomes were formed in excess triolein with the triblock-copolymer Pluronic® P94 as the primary surfactant. Stabilisation was achieved with a molecular stabiliser of type polyethylene glycol (PEG)-dipolyhydroxystearate. For the inverse hexosomes in triolein, the possibility of a formulation without any additional stabiliser was explored. It was found that a sufficiently strong stabilisation effect was created by the primary surfactant alone. Finally, triolein was replaced with olive oil which also led to the successful formation of inverse hexosomes. As far as we know, there exists no previous contribution about inverse ISAsomes in complex oils such as triolein or plant oils, and the existence of stabiliser-free (i.e., self-stabilising) inverse hexosomes has also not been reported until now.

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Self-assembly of stimuli-responsive block copolymers in aqueous solutions: an overview

Cited by 27 publications

References 153 publications

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems

Double hydrophilic copolymers – synthetic approaches, architectural variety, and current application fields

Inverse ISAsomes in Bio-Compatible Oils—Exploring Formulations in Squalane, Triolein and Olive Oil

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Self-assembly of stimuli-responsive block copolymers in aqueous solutions: an overview

Cited by 27 publications

References 153 publications

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG400, PE62, L64, L35, PEG400, PEG600, or PEG1000 + Water Systems

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG400, PE62, L64, L35, PEG400, PEG600, or PEG1000 + Water Systems

Double hydrophilic copolymers – synthetic approaches, architectural variety, and current application fields

Inverse ISAsomes in Bio-Compatible Oils—Exploring Formulations in Squalane, Triolein and Olive Oil

Contact Info

Product

Resources

About

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems

Density, Refractive Index, pH, and Cloud Point Temperature Measurements and Thermal Expansion Coefficient Calculation for PPG₄₀₀, PE62, L64, L35, PEG₄₀₀, PEG₆₀₀, or PEG₁₀₀₀ + Water Systems