Self-assembly of dipeptide Boc-diphenylalanine nanotubes inside electrospun polymeric fibers with strong piezoelectric response

Abstract

Dipeptide electrospun biomaterials are strong piezoelectric materials that can convert applied mechanical forces into electricity.

Self-assembly of Boc-p-nitro-l-phenylalanyl-p-nitro-l-phenylalanine and Boc-l-phenylalanyl-l-tyrosine in solution and into piezoelectric electrospun fibers

“…1 a) and b), according with previously reported formation of highly ordered tubular structures. 16,19 However, this dipeptide also self-assembles into spheres with diameters ranging from nm to µm, when dissolved in high concentrated solutions of HFP with subsequent dilution in ethanol.…”

“…[14][15] Boc-PhePhe when incorporated into electrospun fibers exhibited strong piezoelectric properties. 16 The peptide Boc-pNPhepNPhe peptide was reported to self-assemble into nanofibril and nanospheres. 17 In this work we report the self-assembling of two Boc protected analogues of PhePhe dipeptide: Boc-p-nitro-Lphenylalanyl-p-nitro-L-phenylalanine (Boc-pNPhepNPhe) and Boc-L-phenylalanyl-L-tyrosine (Boc-PheTyr) in solutions of 1,1,1,3,3,3-hexafluoro-2-propanol (HFP) with water or ethanol (0.2/9.8 v/v).…”

Anisotropic PCL nanofibers embedded with nonlinear nanocrystals as strong generators of polarized second harmonic light and piezoelectric currents

“…3NA (present work) 0.12 7.0 P(VDF_TrFe) 34 4.40 1.5 DabcoHReO 4 (ref. 19) 0.02 0.12 Boc-Phe-Phe 35 2…”

Progress in lead-free piezoelectric nanofiller materials and related composite nanogenerator devices

“…42,43 for unprecedented levels of new piezoelectric properties. [44][45][46][47] It is important to note that the underlying physics in and related electromechanical coupling mechanisms for such new material systems, which are complex and not fully understood, need to be claried further through more systematic investigations to enhance our understanding in this research eld. 48 Even though there have been a number of reviews on leadfree piezoelectric nanomaterials due to high potentials for future eco-friendly and biocompatible electronic applications, 11,49,50 the understanding and the control of piezoelectric material properties at nanometer-scale are still at a very basic level, with the majority of reports just focusing on overcoming the processing difficulties.…”