Self‐Assembled Structures with Liquid‐Crystalline Order in Aqueous Solution by Patterning Poly(phenylene ethynylene)s

Kim, Tae-Hyung; Arnt, Lachelle; Atkins, E. D. T.; Tew, Gregory N.

doi:10.1002/chem.200501283

Cited by 12 publications

(7 citation statements)

References 24 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At 20 mN/m, the fit gave a similar ρ el value of 0.414 ± 0.003 e - /Å 3 , but the thickness increased to 15.34 ± 0.09 Å, with a single roughness of 3.68 ± 0.01 Å. A layer thickness of 13−15 Å agrees well with predictions from molecular models and powder X-ray diffraction . GIXD measurements were performed at both pressures but no diffraction peaks were observed for either case, indicating the lack of any in-plane ordering.…”

Section: Resultssupporting

confidence: 70%

Amphiphilic Poly(phenyleneethynylene)s Can Mimic Antimicrobial Peptide Membrane Disordering Effect by Membrane Insertion

et al. 2006

Self Cite

View full text Add to dashboard Cite

Antimicrobial peptides (AMPs) are a class of peptides that are innate to various organisms and function as a defense agent against harmful microorganisms by means of membrane disordering. Characteristic chemical and structural properties of AMPs allow selective interaction and subsequent disruption of invaders' cell membranes. Polymers based on m-phenylene ethynylenes (mPE) were designed and synthesized to mimic the amphiphilic, cationic, and rigid structure of AMPs and were found to be good mimics of AMPs in terms of their high potency toward microbes and low hemolytic activities. Using a Langmuir monolayer insertion assay, two mPEs are found to readily insert into anionic model bacterial membranes but to differ in the degree of selectivity between bacterial and mammalian erythrocyte model membranes. Comparison of grazing incidence X-ray diffraction (GIXD) data before and after the insertion of mPE clearly indicates that the insertion of mPE disrupts lipid packing, altering the tilt of the lipid tail. X-ray reflectivity (XR) measurements of the lipid/mPE system demonstrate that mPE molecules insert through the headgroup region and partially into the tail group region, thus accounting for the observed disordering of tail packing. This study demonstrates that mPEs can mimic AMP's membrane disordering.

show abstract

Section: Resultssupporting

confidence: 70%

Amphiphilic Poly(phenyleneethynylene)s Can Mimic Antimicrobial Peptide Membrane Disordering Effect by Membrane Insertion

et al. 2006

Self Cite

View full text Add to dashboard Cite

show abstract

“…The dependence of the phase behaviour on the sidechain length and density is consistent with experimental studies on systems such as poly(phenylene ethynylenes) [40], poly-glutamates [41], or rigid-rod polyesters [12]. The RDFs for T * = 0.5 are shown in Fig.…”

Section: Resultssupporting

confidence: 86%

Molecular structure and phase behaviour of hairy-rod polymers

Cheung

Troisi

2009

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

Using dissipative particle dynamics simulations the relationship between molecular architecture and phase behaviour in model hairy-rod polymers is studied. In agreement with experimental and theoretical studies the phase behaviour is controlled by changes to the molecular structure, particularly the sidechain length and density, and the molecular interactions. For dense sidechains a lamellar structure is found, which becomes an inverted cylindrical phase when the sidechain density is lowered. The ordered phases become more stable on increasing sidechain length and on increasing the repulsion strength between the backbone and sidechains. In the absence of torsional potentials the structures are double-walled, i.e. layers are two polymer backbones thick, while single-walled structures are observed for polymers with torsional potentials

show abstract

“…54). [183][184][185][186] Also Lam Sm and correlated layer structures (Col rec phases) were observed if a regular sequence of different building blocks is incorporated in the polymer backbones. 184,187,188 Further reducing the number of lateral chains or reducing their length leads to hexagonal honeycomb structures.…”

Section: Lc Phases Of Rod-like Polymers With Lateral Chainsmentioning

confidence: 99%

Liquid crystal engineering – new complex mesophase structures and their relations to polymer morphologies, nanoscale patterning and crystal engineering

2007

View full text Add to dashboard Cite

This critical review focuses on recent progress in the field of T-shaped ternary amphiphiles. These molecules can self-assemble into a series of new liquid crystalline (LC) phases with polygonal cylinder structures, new lamellar phases and LC phases combining columns and layers. These structures are analyzed on the basis of symmetry, net topology and tiling pattern (Laves and Archimedean tilings) and discussed in relation to morphologies of multiblock copolymers, self organized DNA super-lattices, metal-organic frameworks, crystal-engineering and self-assembled periodic superstructures on surfaces (210 references).

show abstract

Self‐Assembled Structures with Liquid‐Crystalline Order in Aqueous Solution by Patterning Poly(phenylene ethynylene)s

Cited by 12 publications

References 24 publications

Amphiphilic Poly(phenyleneethynylene)s Can Mimic Antimicrobial Peptide Membrane Disordering Effect by Membrane Insertion

Amphiphilic Poly(phenyleneethynylene)s Can Mimic Antimicrobial Peptide Membrane Disordering Effect by Membrane Insertion

Molecular structure and phase behaviour of hairy-rod polymers

Liquid crystal engineering – new complex mesophase structures and their relations to polymer morphologies, nanoscale patterning and crystal engineering

Contact Info

Product

Resources

About