2019
DOI: 10.3390/genes10020114
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Self-Adjusting Ant Colony Optimization Based on Information Entropy for Detecting Epistatic Interactions

Abstract: The epistatic interactions of single nucleotide polymorphisms (SNPs) are considered to be an important factor in determining the susceptibility of individuals to complex diseases. Although many methods have been proposed to detect such interactions, the development of detection algorithm is still ongoing due to the computational burden in large-scale association studies. In this paper, to deal with the intensive computing problem of detecting epistatic interactions in large-scale datasets, a self-adjusting ant… Show more

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Cited by 19 publications
(10 citation statements)
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“…Sun et al adopted the fitness function Svalue, path selection and memory-based strategy to enhance the power [30], and then, introduced heuristic information in ACO for identifying epistasis [31]. Guan and Zhao proposed a self-adjusting ACO-based information entropy to identify epistatic interactions [32]. Shang et al systematically reviewed 25 ACO-based epistasis interaction approaches [23].…”
Section: Ant Colony Optimization (Aco)mentioning
confidence: 99%
“…Sun et al adopted the fitness function Svalue, path selection and memory-based strategy to enhance the power [30], and then, introduced heuristic information in ACO for identifying epistasis [31]. Guan and Zhao proposed a self-adjusting ACO-based information entropy to identify epistatic interactions [32]. Shang et al systematically reviewed 25 ACO-based epistasis interaction approaches [23].…”
Section: Ant Colony Optimization (Aco)mentioning
confidence: 99%
“…Sun et al [ 36 ] used multiple ant colonies for the solution and determined strategies for information exchange among ant colonies according to the information entropy of each population to guarantee the balance of its convergence and diversity. Guan et al [ 37 ] used information entropy to choose the positive or negative feedback strategy. A repulsive operator was used in literature [ 38 ] used to improve the ant colony algorithm.…”
Section: Introductionmentioning
confidence: 99%
“…However, there still exists the disadvantage of slow convergence speed or easily falling into local optimum values to optimize large-scale problems. Inspired by the literature [ 36 , 37 , 38 , 39 , 40 ], various types of operators are beneficial to optimize pheromone update strategy, and information entropy can classify the population. Therefore, this paper proposes a new dual operator and dual population ant colony (DODPACO) algorithm to achieve the goals of accelerating convergence and improving the quality of the solution.…”
Section: Introductionmentioning
confidence: 99%
“…AntEpiSeeker [ 23 ] detects disease-associated SNP-SNP interactions by using a two-stage ant colony optimization (ACO) [ 24 , 25 ]. IEACO [ 26 ] automatically adjusts path selection strategies using information entropy to detect SNP-SNP interactions. DESeeker [ 27 ] uses a two-stage differential evolution (DE) [ 28 , 29 ] algorithm to identify the SNP-SNP interaction.…”
Section: Introductionmentioning
confidence: 99%